Two-sided function of osteopontin during osteoblast differentiation

Osteopontin (OPN) is expressed in various cell types including osteoblasts. OPN expression level is robustly increased during osteoblast differentiation. Although OPN was initially found as a secretory protein (sOPN), recent reports identified the intracellular isoform of OPN (iOPN). Distinct functi...

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Veröffentlicht in:	Journal of biochemistry (Tokyo) 2024-12
Hauptverfasser:	Mardiyantoro, Fredy, Chiba, Norika, Seong, Chang-Hwan, Tada, Ryohei, Ohnishi, Tomokazu, Nakamura, Norifumi, Matsuguchi, Tetsuya
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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