Anti-panic effect of fluoxetine during late diestrus in female rats is mediated through GABAergic mechanisms in the dorsal periaqueductal gray

Panic disorder is more frequent in women than in men. In women, vulnerability to panic is enhanced during the late luteal phase of the menstrual cycle. At this time secretion of progesterone and its neuroactive metabolite allopregnanolone (ALLO), which acts as a positive allosteric modulator of the...

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Veröffentlicht in:Neuroscience letters 2024-12, Vol.845, p.138078
Hauptverfasser: Batistela, Matheus F, Hernandes, Paloma M, Frias, Alana T, Lovick, Thelma A, Zangrossi, Jr, Helio
Format: Artikel
Sprache:eng
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