Ageing drop by drop: Disturbance of the membrane-less organelle biogenesis as an aging hallmark

Despite extensive research, the features associated with the aging phenotype are not all-inclusive and need to be updated on a regular basis to incorporate new findings. We propose to include the dysfunction of membrane-less organelle (MLO) as a new aging hallmark. Special scaffold proteins with a h...

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Veröffentlicht in:	Biochemical and biophysical research communications 2025-01, Vol.742, p.151088, Article 151088
Hauptverfasser:	Saqr, Baraa M.G.A., Kotoyants, Nikolay O., Nesterov, Semen V., Manuylov, Vladimir D., Dayhoff, Guy W., Fonin, Alexander V., Turoverov, Konstantin K., Kuznetsova, Irina M., Gordeliy, Valentin I., Ilyinsky, Nikolay S., Uversky, Vladimir N.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - metabolism Computational Biology - methods Humans Organelle Biogenesis Organelles - metabolism
Online-Zugang:	Volltext
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