Ru@UiO-66-NH 2 MOFs-Based Dual Emission Ratiometric Fluorescence for Sensitive Sensing of Arginine
Arginine has been widely applied in the food industry as coloring agents, flavoring agents, and nutritional fortifiers. It is also one of the major components of feed additives. Currently, methods for the highly selective detection of arginine remain absent. For accurate and sensitive detection of L...
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| Veröffentlicht in: | Biosensors (Basel) 2024-10, Vol.14 (10) |
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| creator | Fan, Jiawen Qi, Junjie Li, Jingkun Pi, Fuwei |
| description | Arginine has been widely applied in the food industry as coloring agents, flavoring agents, and nutritional fortifiers. It is also one of the major components of feed additives. Currently, methods for the highly selective detection of arginine remain absent. For accurate and sensitive detection of L-arginine, a novel ratiometric fluorescence assay based on Ru@UiO-66-NH
was developed and demonstrated in this study. Under optimized detection conditions, the limit of detection (LOD) of this assay for L-arginine was 2.32 μM, which is superior to most assays reported to date. Meanwhile, Ru@UiO-66-NH
showed good stability within 30 days, demonstrating the wide applicability of the proposed assay. The spike-and-recovery rates of the proposed assay for L-arginine in real samples (e.g., tea, grape juice, and serum) were 84.27-113.09%. Overall, the proposed assay showed high sensitivity, good reproducibility, and excellent stability in the detection of L-arginine in both buffer and real samples. |
| doi_str_mv | 10.3390/bios14100512 |
| format | Article |
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was developed and demonstrated in this study. Under optimized detection conditions, the limit of detection (LOD) of this assay for L-arginine was 2.32 μM, which is superior to most assays reported to date. Meanwhile, Ru@UiO-66-NH
showed good stability within 30 days, demonstrating the wide applicability of the proposed assay. The spike-and-recovery rates of the proposed assay for L-arginine in real samples (e.g., tea, grape juice, and serum) were 84.27-113.09%. Overall, the proposed assay showed high sensitivity, good reproducibility, and excellent stability in the detection of L-arginine in both buffer and real samples.</description><identifier>EISSN: 2079-6374</identifier><identifier>DOI: 10.3390/bios14100512</identifier><identifier>PMID: 39451725</identifier><language>eng</language><publisher>Switzerland</publisher><subject>Arginine - analysis ; Biosensing Techniques ; Fluorescence ; Fruit and Vegetable Juices - analysis ; Limit of Detection ; Reproducibility of Results ; Ruthenium - chemistry ; Spectrometry, Fluorescence ; Tea - chemistry</subject><ispartof>Biosensors (Basel), 2024-10, Vol.14 (10)</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,860,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/39451725$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fan, Jiawen</creatorcontrib><creatorcontrib>Qi, Junjie</creatorcontrib><creatorcontrib>Li, Jingkun</creatorcontrib><creatorcontrib>Pi, Fuwei</creatorcontrib><title>Ru@UiO-66-NH 2 MOFs-Based Dual Emission Ratiometric Fluorescence for Sensitive Sensing of Arginine</title><title>Biosensors (Basel)</title><addtitle>Biosensors (Basel)</addtitle><description>Arginine has been widely applied in the food industry as coloring agents, flavoring agents, and nutritional fortifiers. It is also one of the major components of feed additives. Currently, methods for the highly selective detection of arginine remain absent. For accurate and sensitive detection of L-arginine, a novel ratiometric fluorescence assay based on Ru@UiO-66-NH
was developed and demonstrated in this study. Under optimized detection conditions, the limit of detection (LOD) of this assay for L-arginine was 2.32 μM, which is superior to most assays reported to date. Meanwhile, Ru@UiO-66-NH
showed good stability within 30 days, demonstrating the wide applicability of the proposed assay. The spike-and-recovery rates of the proposed assay for L-arginine in real samples (e.g., tea, grape juice, and serum) were 84.27-113.09%. Overall, the proposed assay showed high sensitivity, good reproducibility, and excellent stability in the detection of L-arginine in both buffer and real samples.</description><subject>Arginine - analysis</subject><subject>Biosensing Techniques</subject><subject>Fluorescence</subject><subject>Fruit and Vegetable Juices - analysis</subject><subject>Limit of Detection</subject><subject>Reproducibility of Results</subject><subject>Ruthenium - chemistry</subject><subject>Spectrometry, Fluorescence</subject><subject>Tea - chemistry</subject><issn>2079-6374</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFjjtvwjAURi2kClBhY0b3D7i14yRWtr6IWACJx4yccINuldjIN6nUf99Kbed-yznDGT4hFlo9GFOox4oC61QrlelkJKaJsoXMjU0nYs78rr5nU1sYOxYTU6SZtkk2FdV-eDrRTua53K4hgc2uZPniGC_wNrgWVh0xU_Cwdz2FDvtINZTtECJyjb5GaEKEA3qmnj7wx_wVQgPP8UqePM7EXeNaxvkv78WyXB1f1_I2VB1ezrdInYuf579T5t_gC1WRRpM</recordid><startdate>20241021</startdate><enddate>20241021</enddate><creator>Fan, Jiawen</creator><creator>Qi, Junjie</creator><creator>Li, Jingkun</creator><creator>Pi, Fuwei</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>20241021</creationdate><title>Ru@UiO-66-NH 2 MOFs-Based Dual Emission Ratiometric Fluorescence for Sensitive Sensing of Arginine</title><author>Fan, Jiawen ; Qi, Junjie ; Li, Jingkun ; Pi, Fuwei</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-pubmed_primary_394517253</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2024</creationdate><topic>Arginine - analysis</topic><topic>Biosensing Techniques</topic><topic>Fluorescence</topic><topic>Fruit and Vegetable Juices - analysis</topic><topic>Limit of Detection</topic><topic>Reproducibility of Results</topic><topic>Ruthenium - chemistry</topic><topic>Spectrometry, Fluorescence</topic><topic>Tea - chemistry</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fan, Jiawen</creatorcontrib><creatorcontrib>Qi, Junjie</creatorcontrib><creatorcontrib>Li, Jingkun</creatorcontrib><creatorcontrib>Pi, Fuwei</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Biosensors (Basel)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fan, Jiawen</au><au>Qi, Junjie</au><au>Li, Jingkun</au><au>Pi, Fuwei</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Ru@UiO-66-NH 2 MOFs-Based Dual Emission Ratiometric Fluorescence for Sensitive Sensing of Arginine</atitle><jtitle>Biosensors (Basel)</jtitle><addtitle>Biosensors (Basel)</addtitle><date>2024-10-21</date><risdate>2024</risdate><volume>14</volume><issue>10</issue><eissn>2079-6374</eissn><abstract>Arginine has been widely applied in the food industry as coloring agents, flavoring agents, and nutritional fortifiers. It is also one of the major components of feed additives. Currently, methods for the highly selective detection of arginine remain absent. For accurate and sensitive detection of L-arginine, a novel ratiometric fluorescence assay based on Ru@UiO-66-NH
was developed and demonstrated in this study. Under optimized detection conditions, the limit of detection (LOD) of this assay for L-arginine was 2.32 μM, which is superior to most assays reported to date. Meanwhile, Ru@UiO-66-NH
showed good stability within 30 days, demonstrating the wide applicability of the proposed assay. The spike-and-recovery rates of the proposed assay for L-arginine in real samples (e.g., tea, grape juice, and serum) were 84.27-113.09%. Overall, the proposed assay showed high sensitivity, good reproducibility, and excellent stability in the detection of L-arginine in both buffer and real samples.</abstract><cop>Switzerland</cop><pmid>39451725</pmid><doi>10.3390/bios14100512</doi></addata></record> |
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| source | MEDLINE; DOAJ Directory of Open Access Journals; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central Open Access; MDPI - Multidisciplinary Digital Publishing Institute; PubMed Central |
| subjects | Arginine - analysis Biosensing Techniques Fluorescence Fruit and Vegetable Juices - analysis Limit of Detection Reproducibility of Results Ruthenium - chemistry Spectrometry, Fluorescence Tea - chemistry |
| title | Ru@UiO-66-NH 2 MOFs-Based Dual Emission Ratiometric Fluorescence for Sensitive Sensing of Arginine |
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