Reaction mechanisms of trans-9,10-dihydroxy-anti-7,8-epoxy-7,8,9,10-tetrahydro-3-methylcho lan threne with DNA in aqueous solutions. Conformation of adducts

The reaction mechanisms of trans-9,10-dihydroxy-anti-7,8-epoxy-7,8,9,10-tetrahydro-3-methylcholanth rene (anti-3-MCDE) in aqueous phosphate buffer solutions (pH 7, 24 degrees C) containing double-stranded DNA, and the structure of the covalent adduct formed, were studied by utilizing the techniques...

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Veröffentlicht in:Carcinogenesis (New York) 1986-01, Vol.7 (1), p.41
Hauptverfasser: Kim, M H, Geacintov, N E, McQuillen, D G, Pope, M, Harvey, R G
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Sprache:eng
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