Experimental VLP vaccine displaying a furin antigen elicits production of autoantibodies and is well tolerated in mice

Proprotein convertase (PCSK) enzymes serve a wide range of regulatory roles in mammals, for example in metabolism and immunity, and altered activity of PCSKs is associated with disorders, such as cardiovascular disease and cancer. Inhibition of PCSK9 activity with therapeutic antibodies or small int...

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Veröffentlicht in:	Nanoscale advances 2024-12, Vol.6 (24), p.6239-6252
Hauptverfasser:	Lampinen, Vili, Ojanen, Markus J. T, Caro, Fernanda Muñoz, Gröhn, Stina, Hankaniemi, Minna M, Pesu, Marko, Hytönen, Vesa P
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry
Online-Zugang:	Volltext
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