Tamoxifen and Oligospermia
Thirty normogonadotropic oligospermic males were administered Tamoxifen (20 mg/day) for 4 months. A complete evaluation of seminal parameters before and after treatment was performed. An increase of both mean sperm concentration and total sperm count was noted after treatment with Tamoxifen (p <...
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| Veröffentlicht in: | Archives of andrology 1985, Vol.15 (1), p.83-88 |
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| container_title | Archives of andrology |
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| creator | Noci, I. Chelo, E. Saltarelli, O. Donaticori, G. Scarselli, G. |
| description | Thirty normogonadotropic oligospermic males were administered Tamoxifen (20 mg/day) for 4 months. A complete evaluation of seminal parameters before and after treatment was performed. An increase of both mean sperm concentration and total sperm count was noted after treatment with Tamoxifen (p < 0.05), whereas no variation was observed for semen volume, sperm morphologic characteristics, or sperm motility. Hormonal patterns of 5 of these subjects before, during, and after 3 months of treatment with Tamoxifen showed a progressive increase of gonadotropin (especially LH) and 17/βE2 values; testosterone variations were minimal, and PRL showed a slight decrease. |
| doi_str_mv | 10.3109/01485018508986896 |
| format | Article |
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A complete evaluation of seminal parameters before and after treatment was performed. An increase of both mean sperm concentration and total sperm count was noted after treatment with Tamoxifen (p < 0.05), whereas no variation was observed for semen volume, sperm morphologic characteristics, or sperm motility. Hormonal patterns of 5 of these subjects before, during, and after 3 months of treatment with Tamoxifen showed a progressive increase of gonadotropin (especially LH) and 17/βE2 values; testosterone variations were minimal, and PRL showed a slight decrease.</description><identifier>ISSN: 0148-5016</identifier><identifier>EISSN: 1521-0375</identifier><identifier>DOI: 10.3109/01485018508986896</identifier><identifier>PMID: 3938205</identifier><language>eng</language><publisher>England: Informa UK Ltd</publisher><subject>Adult ; Estradiol - blood ; Follicle Stimulating Hormone - blood ; Humans ; Luteinizing Hormone - blood ; Male ; Oligospermia ; Oligospermia - blood ; Oligospermia - drug therapy ; Prolactin - blood ; Sperm Count ; Tamoxifen ; Tamoxifen - therapeutic use ; Testosterone - blood</subject><ispartof>Archives of andrology, 1985, Vol.15 (1), p.83-88</ispartof><rights>1985 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1985</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c471t-da91a60cf55155f02dc5f8cbacf5669f5f0bbcb265cbc847503856d47b50e70a3</citedby><cites>FETCH-LOGICAL-c471t-da91a60cf55155f02dc5f8cbacf5669f5f0bbcb265cbc847503856d47b50e70a3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.tandfonline.com/doi/pdf/10.3109/01485018508986896$$EPDF$$P50$$Ginformaworld$$H</linktopdf><linktohtml>$$Uhttps://www.tandfonline.com/doi/full/10.3109/01485018508986896$$EHTML$$P50$$Ginformaworld$$H</linktohtml><link.rule.ids>314,776,780,4010,27902,27903,27904,59623,59729,60412,60518,61197,61232,61378,61413</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/3938205$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Noci, I.</creatorcontrib><creatorcontrib>Chelo, E.</creatorcontrib><creatorcontrib>Saltarelli, O.</creatorcontrib><creatorcontrib>Donaticori, G.</creatorcontrib><creatorcontrib>Scarselli, G.</creatorcontrib><title>Tamoxifen and Oligospermia</title><title>Archives of andrology</title><addtitle>Arch Androl</addtitle><description>Thirty normogonadotropic oligospermic males were administered Tamoxifen (20 mg/day) for 4 months. A complete evaluation of seminal parameters before and after treatment was performed. An increase of both mean sperm concentration and total sperm count was noted after treatment with Tamoxifen (p < 0.05), whereas no variation was observed for semen volume, sperm morphologic characteristics, or sperm motility. Hormonal patterns of 5 of these subjects before, during, and after 3 months of treatment with Tamoxifen showed a progressive increase of gonadotropin (especially LH) and 17/βE2 values; testosterone variations were minimal, and PRL showed a slight decrease.</description><subject>Adult</subject><subject>Estradiol - blood</subject><subject>Follicle Stimulating Hormone - blood</subject><subject>Humans</subject><subject>Luteinizing Hormone - blood</subject><subject>Male</subject><subject>Oligospermia</subject><subject>Oligospermia - blood</subject><subject>Oligospermia - drug therapy</subject><subject>Prolactin - blood</subject><subject>Sperm Count</subject><subject>Tamoxifen</subject><subject>Tamoxifen - therapeutic use</subject><subject>Testosterone - blood</subject><issn>0148-5016</issn><issn>1521-0375</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1985</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kF1LwzAUhoMoc05_gIKwK--qJ22TpuiNDL9gsJt5HU7TxHW0zUxadP_ejBVBRC8OB877weEh5JzCdUIhvwGaCgY0jMgFFzk_IGPKYhpBkrFDMt7pUTDwY3Li_RoAYsZhREZJnogY2JhcLLGxn5XR7RTbcrqoqzfrN9o1FZ6SI4O112fDnpDXx4fl7DmaL55eZvfzSKUZ7aISc4oclGGMMmYgLhUzQhUYLpznJpyKQhUxZ6pQIs0YJILxMs0KBjoDTCbkat-7cfa9176TTeWVrmtste29zDiPQXAejHRvVM5677SRG1c16LaSgtzxkL94hMzlUN4XjS6_EwOAoN_t9ao11jX4YV1dyg63tXXGYasqv6v-u_72R3ylse5WCp2Wa9u7NnD757kvzQJ-vA</recordid><startdate>1985</startdate><enddate>1985</enddate><creator>Noci, I.</creator><creator>Chelo, E.</creator><creator>Saltarelli, O.</creator><creator>Donaticori, G.</creator><creator>Scarselli, G.</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1985</creationdate><title>Tamoxifen and Oligospermia</title><author>Noci, I. ; Chelo, E. ; Saltarelli, O. ; Donaticori, G. ; Scarselli, G.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c471t-da91a60cf55155f02dc5f8cbacf5669f5f0bbcb265cbc847503856d47b50e70a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1985</creationdate><topic>Adult</topic><topic>Estradiol - blood</topic><topic>Follicle Stimulating Hormone - blood</topic><topic>Humans</topic><topic>Luteinizing Hormone - blood</topic><topic>Male</topic><topic>Oligospermia</topic><topic>Oligospermia - blood</topic><topic>Oligospermia - drug therapy</topic><topic>Prolactin - blood</topic><topic>Sperm Count</topic><topic>Tamoxifen</topic><topic>Tamoxifen - therapeutic use</topic><topic>Testosterone - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Noci, I.</creatorcontrib><creatorcontrib>Chelo, E.</creatorcontrib><creatorcontrib>Saltarelli, O.</creatorcontrib><creatorcontrib>Donaticori, G.</creatorcontrib><creatorcontrib>Scarselli, G.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of andrology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Noci, I.</au><au>Chelo, E.</au><au>Saltarelli, O.</au><au>Donaticori, G.</au><au>Scarselli, G.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Tamoxifen and Oligospermia</atitle><jtitle>Archives of andrology</jtitle><addtitle>Arch Androl</addtitle><date>1985</date><risdate>1985</risdate><volume>15</volume><issue>1</issue><spage>83</spage><epage>88</epage><pages>83-88</pages><issn>0148-5016</issn><eissn>1521-0375</eissn><abstract>Thirty normogonadotropic oligospermic males were administered Tamoxifen (20 mg/day) for 4 months. A complete evaluation of seminal parameters before and after treatment was performed. An increase of both mean sperm concentration and total sperm count was noted after treatment with Tamoxifen (p < 0.05), whereas no variation was observed for semen volume, sperm morphologic characteristics, or sperm motility. Hormonal patterns of 5 of these subjects before, during, and after 3 months of treatment with Tamoxifen showed a progressive increase of gonadotropin (especially LH) and 17/βE2 values; testosterone variations were minimal, and PRL showed a slight decrease.</abstract><cop>England</cop><pub>Informa UK Ltd</pub><pmid>3938205</pmid><doi>10.3109/01485018508986896</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0148-5016 |
| ispartof | Archives of andrology, 1985, Vol.15 (1), p.83-88 |
| issn | 0148-5016 1521-0375 |
| language | eng |
| recordid | cdi_pubmed_primary_3938205 |
| source | MEDLINE; Taylor & Francis Medical Library - CRKN; Taylor & Francis Journals Complete |
| subjects | Adult Estradiol - blood Follicle Stimulating Hormone - blood Humans Luteinizing Hormone - blood Male Oligospermia Oligospermia - blood Oligospermia - drug therapy Prolactin - blood Sperm Count Tamoxifen Tamoxifen - therapeutic use Testosterone - blood |
| title | Tamoxifen and Oligospermia |
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