Multicenter Study of the Clinical Efficacy of Imipenem/Cilastatin for Treatment of Serious Infections

The efficacy and safety of imipenem/cilastatin was evaluated in a multicenter study. For 49 of the 78 patients with 79 infections entered into the study, the clinical and bacteriologic efficacy of therapy could be evaluated. Toxicity data were analyzed for all 79 infections. Overall, 35 of 49 infect...

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Veröffentlicht in:	Reviews of infectious diseases 1985-07, Vol.7, p.S476-S481
Hauptverfasser:	David Trumbore, Raymond Pontzer, Matthew E. Levison, Donald Kaye, Michael Cynamon, Liu, Chien, Daniel R. Hinthorn, James S. Tan, Thomas M. File
Format:	Artikel
Sprache:	eng
Schlagworte:	Abscesses Adult Aged Bacterial Infections - drug therapy Blood Cilastatin Clinical Trials as Topic Cyclopropanes - administration & dosage Cyclopropanes - adverse effects Digestive System - drug effects Dosage Drug Resistance, Microbial Drug Therapy, Combination Female Humans Imipenem Infections Male Middle Aged Osteomyelitis Osteomyelitis - drug therapy Pathogens Pneumonia - drug therapy Pseudomonas aeruginosa Pseudomonas Infections - drug therapy Pyelonephritis Pyelonephritis - drug therapy Relapse Sepsis - drug therapy Session IV: Clinical Efficacy and Safety of Imipenem/Cilastatin Skin Diseases, Infectious - drug therapy Streptococcus Superinfection Thienamycins - administration & dosage Thienamycins - adverse effects
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