Coordination compounds of cobalt() with carboxylate non-steroidal anti-inflammatory drugs: structure and biological profile

Fourteen cobalt( ii ) complexes with the non-steroidal anti-inflammatory drugs sodium meclofenamate, tolfenamic acid, mefenamic acid, naproxen, sodium diclofenac, and diflunisal were prepared in the presence or absence of a series of nitrogen-donors (namely imidazole, pyridine, 3-aminopyridine, neoc...

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Veröffentlicht in:	Dalton transactions : an international journal of inorganic chemistry 2024-09, Vol.53 (36), p.15215-15235
Hauptverfasser:	Perontsis, Spyros, Hatzidimitriou, Antonios G, Psomas, George
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anti-inflammatory agents Anti-Inflammatory Agents, Non-Steroidal - chemistry Anti-Inflammatory Agents, Non-Steroidal - pharmacology Antioxidants Antioxidants - chemistry Antioxidants - pharmacology Binding sites Cattle Cobalt - chemistry Cobalt compounds Coordination Complexes - chemical synthesis Coordination Complexes - chemistry Coordination Complexes - pharmacology Coordination compounds Crystal structure Crystallography Crystallography, X-Ray Diclofenac - chemistry Diclofenac - pharmacology Diflunisal - chemistry Diflunisal - pharmacology DNA - chemistry DNA - metabolism Free radicals Humans Hydrogen peroxide Imidazole Meclofenamic Acid - chemistry Meclofenamic Acid - pharmacology Mefenamic Acid - chemistry Mefenamic Acid - pharmacology Naproxen - chemistry Naproxen - pharmacology ortho-Aminobenzoates - chemistry ortho-Aminobenzoates - pharmacology Plasmids Scavenging Serum albumin Serum Albumin, Bovine - chemistry Serum Albumin, Bovine - metabolism Single crystals Sodium Sulfonic acid
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