PYTA: a universal chelator for advancing the theranostic palette of nuclear medicine

To clinically advance the growing arsenal of radiometals available to image and treat cancer, chelators with versatile binding properties are needed. Herein, we evaluated the ability of the py 2 [18]dieneN 6 macrocycle PYTA to interchangeably bind and stabilize 225 Ac 3+ , [ 177 Lu]Lu 3+ , [ 111 In]...

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Veröffentlicht in:	Chemical science (Cambridge) 2024-07, Vol.15 (29), p.11279-11286
Hauptverfasser:	Simms, Megan E, Li, Zhiyao, Sibley, Megan M, Ivanov, Alexander S, Lara, Caroline M, Johnstone, Timothy C, Kertesz, Vilmos, Fears, Amanda, White, Frankie D, Thorek, Daniel L. J, Thiele, Nikki A
Format:	Artikel
Sprache:	eng
Schlagworte:	Chelating agents Chemistry Computed tomography In vivo methods and tests Medical imaging NMR spectroscopy Nuclear medicine Photon emission Positron emission Radioisotopes Radiolabelling RADIOLOGY AND NUCLEAR MEDICINE Room temperature Tomography X ray imagery
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