Astrocyte-specific inhibition of sigma-1 receptor leads to depressive-like behaviors in mice via activation of NF-κB-induced neuroinflammation

Major depressive disorder (MDD) is a global health burden characterized by persistent low mood, deprivation of pleasure, recurrent thoughts of death, and physical and cognitive deficits. The current understanding of the pathophysiology of MDD is lacking, resulting in few rapid and effective antidepr...

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Veröffentlicht in:	Brain, behavior, and immunity behavior, and immunity, 2024-08
Hauptverfasser:	Wang, Jing-Ya, Ren, Peng, Cui, Lin-Yu, Duan, Jing-Yao, Chen, Hong-Lei, Zeng, Zhi-Rui, Li, Yun-Feng
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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