Plasma sFlt-1/PlGF ratio of 11.5 multiples of median predicts preeclampsia with severe features within two weeks of testing

Angiogenic imbalances, characterized by an excess of antiangiogenic factors (soluble fms-like tyrosine kinase 1 [sFlt-1]) and reduced angiogenic factors (VEGF and placental growth factor [PlGF]), contribute to the mechanisms of disease in preeclampsia. The ratio of sFlt-1 to PlGF has been used as a...

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Veröffentlicht in:American journal of obstetrics and gynecology 2024-05
Hauptverfasser: Espinoza, Jimmy, Calsavara, Vinicius F, Kilpatrick, Sarah, Rana, Sarosh, Costantine, Maged M, Boggess, Kim, Wylie, Blair J, Moore Simas, Tiffany A, Louis, Judette M, Gaw, Stephanie L, Murtha, Amy, Wiegand, Samantha, Gollin, Yvonne, Singh, Deepjot, Silver, Robert M, Durie, Danielle E, Panda, Britta, Norwitz, Errol R, Burd, Irina, Plunkett, Beth, Scott, Rachel K, Lemoine, Elizabeth, Thadhani, Ravi, Karumanchi, S Ananth
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Sprache:eng
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