Polyamines promote xenobiotic nucleic acid synthesis by modified thermophilic polymerase mutants

The enzymatic synthesis of xenobiotic nucleic acids (XNA), which are artificially sugar-modified nucleic acids, is essential for the preparation of XNA libraries. XNA libraries are used in the in vitro selection of XNA aptamers and enzymes (XNAzymes). Efficient enzymatic synthesis of various XNAs ca...

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Veröffentlicht in:	RSC chemical biology 2024-05, Vol.5 (5), p.467-472
Hauptverfasser:	Hoshino, Hidekazu, Kasahara, Yuuya, Obika, Satoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry
Online-Zugang:	Volltext
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