DOI- and TOF-Capable PET Array Detector Using Double-Ended Light Readout and Stripline-Based Row and Column Electronic Readout
We investigate a highly multiplexing readout for depth-of-interaction (DOI) and time-of-flight PET detector consisting of an N\times N crystals whose light outputs at the front and back ends are detected by using silicon photomultipliers (SiPMs). The front N\times N SiPM array is read by using a...
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Veröffentlicht in: | IEEE transactions on radiation and plasma medical sciences 2024-03, Vol.8 (3), p.269-276 |
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creator | Wang, Fei Kao, Chien-Min Zhang, Xiaoyu Liu, Linfeng Hua, Yuexuan Kim, Heejong Choong, Woon-Seng Xie, Qingguo |
description | We investigate a highly multiplexing readout for depth-of-interaction (DOI) and time-of-flight PET detector consisting of an N\times N crystals whose light outputs at the front and back ends are detected by using silicon photomultipliers (SiPMs). The front N\times N SiPM array is read by using a stripline (SL) configured to support discrimination of the row position of the signal-producing crystal. The back N\times N SiPM array is similarly read by an SL for column discrimination. Hence, the detector has only four outputs. We built 4\times4 and 8\times8 detector modules (DMs) by using 3.0-mm ^{3}\,\,\times3.0 -mm ^{3}\,\,\times20 -mm3 lutetium-yttrium oxyorthosilicates. The outputs were sampled and processed offline. For both DMs, crystal discrimination was successful. For the 4 \times 4 DM, we obtained an average energy resolution (ER) of 14.1%, an average DOI resolution of 2.5 mm, a non DOI-corrected coincidence resolving time (CRT), measured in coincidence with a single-pixel reference detector (refDet), of about 495ps. For the 8 \times 8 DM, the average ER, average DOI resolution and average CRT were 16.4%, 2.9 mm, and 641ps, respectively. We identified the intercrystal scattering as a probable cause for the CRT deterioration when the DM was increased from 4 \times 4 to 8 \times 8. |
doi_str_mv | 10.1109/TRPMS.2024.3360942 |
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The front <inline-formula> <tex-math notation="LaTeX">N\times N </tex-math></inline-formula> SiPM array is read by using a stripline (SL) configured to support discrimination of the row position of the signal-producing crystal. The back <inline-formula> <tex-math notation="LaTeX">N\times N </tex-math></inline-formula> SiPM array is similarly read by an SL for column discrimination. Hence, the detector has only four outputs. We built <inline-formula> <tex-math notation="LaTeX">4\times4 </tex-math></inline-formula> and <inline-formula> <tex-math notation="LaTeX">8\times8 </tex-math></inline-formula> detector modules (DMs) by using 3.0-mm<inline-formula> <tex-math notation="LaTeX">^{3}\,\,\times3.0 </tex-math></inline-formula>-mm<inline-formula> <tex-math notation="LaTeX">^{3}\,\,\times20 </tex-math></inline-formula>-mm3 lutetium-yttrium oxyorthosilicates. The outputs were sampled and processed offline. For both DMs, crystal discrimination was successful. For the 4<inline-formula> <tex-math notation="LaTeX">\times </tex-math></inline-formula>4 DM, we obtained an average energy resolution (ER) of 14.1%, an average DOI resolution of 2.5 mm, a non DOI-corrected coincidence resolving time (CRT), measured in coincidence with a single-pixel reference detector (refDet), of about 495ps. For the 8<inline-formula> <tex-math notation="LaTeX">\times </tex-math></inline-formula>8 DM, the average ER, average DOI resolution and average CRT were 16.4%, 2.9 mm, and 641ps, respectively. We identified the intercrystal scattering as a probable cause for the CRT deterioration when the DM was increased from 4<inline-formula> <tex-math notation="LaTeX">\times </tex-math></inline-formula>4 to 8<inline-formula> <tex-math notation="LaTeX">\times </tex-math></inline-formula>8.]]></description><identifier>ISSN: 2469-7311</identifier><identifier>EISSN: 2469-7303</identifier><identifier>DOI: 10.1109/TRPMS.2024.3360942</identifier><identifier>PMID: 38654812</identifier><identifier>CODEN: ITRPFI</identifier><language>eng</language><publisher>United States: IEEE</publisher><subject>Arrays ; Back ; Cathode ray tubes ; Crystals ; Depth-of-interaction (DOI) ; Detectors ; Energy resolution ; Histograms ; Lutetium ; Multiplexing ; PET detector ; Photomultiplier tubes ; Scintillators ; Sensors ; stripline (SL) ; Time measurement ; time of flight (TOF) ; Yttrium</subject><ispartof>IEEE transactions on radiation and plasma medical sciences, 2024-03, Vol.8 (3), p.269-276</ispartof><rights>Copyright The Institute of Electrical and Electronics Engineers, Inc. (IEEE) 2024</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c352t-bf4d6629afa21bf87400fa19a3e25679dfe1f49223734d3d9b2cb295405f42853</citedby><cites>FETCH-LOGICAL-c352t-bf4d6629afa21bf87400fa19a3e25679dfe1f49223734d3d9b2cb295405f42853</cites><orcidid>0000-0002-8229-0720 ; 0000-0001-5353-2201 ; 0009-0000-0900-0216 ; 0000-0002-8785-5225 ; 0000-0003-3372-2803</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://ieeexplore.ieee.org/document/10418168$$EHTML$$P50$$Gieee$$H</linktohtml><link.rule.ids>314,780,784,796,27924,27925,54758</link.rule.ids><linktorsrc>$$Uhttps://ieeexplore.ieee.org/document/10418168$$EView_record_in_IEEE$$FView_record_in_$$GIEEE</linktorsrc><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38654812$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Wang, Fei</creatorcontrib><creatorcontrib>Kao, Chien-Min</creatorcontrib><creatorcontrib>Zhang, Xiaoyu</creatorcontrib><creatorcontrib>Liu, Linfeng</creatorcontrib><creatorcontrib>Hua, Yuexuan</creatorcontrib><creatorcontrib>Kim, Heejong</creatorcontrib><creatorcontrib>Choong, Woon-Seng</creatorcontrib><creatorcontrib>Xie, Qingguo</creatorcontrib><title>DOI- and TOF-Capable PET Array Detector Using Double-Ended Light Readout and Stripline-Based Row and Column Electronic Readout</title><title>IEEE transactions on radiation and plasma medical sciences</title><addtitle>TRPMS</addtitle><addtitle>IEEE Trans Radiat Plasma Med Sci</addtitle><description><![CDATA[We investigate a highly multiplexing readout for depth-of-interaction (DOI) and time-of-flight PET detector consisting of an <inline-formula> <tex-math notation="LaTeX">N\times N </tex-math></inline-formula> crystals whose light outputs at the front and back ends are detected by using silicon photomultipliers (SiPMs). The front <inline-formula> <tex-math notation="LaTeX">N\times N </tex-math></inline-formula> SiPM array is read by using a stripline (SL) configured to support discrimination of the row position of the signal-producing crystal. The back <inline-formula> <tex-math notation="LaTeX">N\times N </tex-math></inline-formula> SiPM array is similarly read by an SL for column discrimination. Hence, the detector has only four outputs. We built <inline-formula> <tex-math notation="LaTeX">4\times4 </tex-math></inline-formula> and <inline-formula> <tex-math notation="LaTeX">8\times8 </tex-math></inline-formula> detector modules (DMs) by using 3.0-mm<inline-formula> <tex-math notation="LaTeX">^{3}\,\,\times3.0 </tex-math></inline-formula>-mm<inline-formula> <tex-math notation="LaTeX">^{3}\,\,\times20 </tex-math></inline-formula>-mm3 lutetium-yttrium oxyorthosilicates. The outputs were sampled and processed offline. For both DMs, crystal discrimination was successful. For the 4<inline-formula> <tex-math notation="LaTeX">\times </tex-math></inline-formula>4 DM, we obtained an average energy resolution (ER) of 14.1%, an average DOI resolution of 2.5 mm, a non DOI-corrected coincidence resolving time (CRT), measured in coincidence with a single-pixel reference detector (refDet), of about 495ps. For the 8<inline-formula> <tex-math notation="LaTeX">\times </tex-math></inline-formula>8 DM, the average ER, average DOI resolution and average CRT were 16.4%, 2.9 mm, and 641ps, respectively. We identified the intercrystal scattering as a probable cause for the CRT deterioration when the DM was increased from 4<inline-formula> <tex-math notation="LaTeX">\times </tex-math></inline-formula>4 to 8<inline-formula> <tex-math notation="LaTeX">\times </tex-math></inline-formula>8.]]></description><subject>Arrays</subject><subject>Back</subject><subject>Cathode ray tubes</subject><subject>Crystals</subject><subject>Depth-of-interaction (DOI)</subject><subject>Detectors</subject><subject>Energy resolution</subject><subject>Histograms</subject><subject>Lutetium</subject><subject>Multiplexing</subject><subject>PET detector</subject><subject>Photomultiplier tubes</subject><subject>Scintillators</subject><subject>Sensors</subject><subject>stripline (SL)</subject><subject>Time measurement</subject><subject>time of flight (TOF)</subject><subject>Yttrium</subject><issn>2469-7311</issn><issn>2469-7303</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2024</creationdate><recordtype>article</recordtype><sourceid>RIE</sourceid><recordid>eNpdkU1r3DAQhkVoSUKaPxBCEfTSi7fSSJatY7q7aQNbNmw2ZyFbo9TBa20lm5JLf3u9HwmlpxGj530YeAm54mzCOdNf1qv7Hw8TYCAnQiimJZyQc5BKZ4Vg4t3bm_MzcpnSM2OMFyVomZ-SM1GqXJYczsmf2fIuo7ZzdL28zaZ2a6sW6f18TW9itC90hj3WfYj0MTXdE52FYfzP5p1DRxfN08-ertC6MPR7x0Mfm23bdJh9tWkkVuH3fj8N7bDp6LwdXTF0Tf2a-kDee9smvDzOC_J4O19Pv2eL5be76c0iq0UOfVZ56ZQCbb0FXvmykIx5y7UVCLkqtPPIvdQAohDSCacrqCvQuWS5l1Dm4oJ8Pni3MfwaMPVm06Qa29Z2GIZkBJMq56KQO_TTf-hzGGI3XmdAi5JxrbgeKThQdQwpRfRmG5uNjS-GM7MryOwLMruCzLGgMfTxqB6qDbq3yGsdI3B9ABpE_McoeclVKf4CxpCSSQ</recordid><startdate>20240301</startdate><enddate>20240301</enddate><creator>Wang, Fei</creator><creator>Kao, Chien-Min</creator><creator>Zhang, Xiaoyu</creator><creator>Liu, Linfeng</creator><creator>Hua, Yuexuan</creator><creator>Kim, Heejong</creator><creator>Choong, Woon-Seng</creator><creator>Xie, Qingguo</creator><general>IEEE</general><general>The Institute of Electrical and Electronics Engineers, Inc. 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The front <inline-formula> <tex-math notation="LaTeX">N\times N </tex-math></inline-formula> SiPM array is read by using a stripline (SL) configured to support discrimination of the row position of the signal-producing crystal. The back <inline-formula> <tex-math notation="LaTeX">N\times N </tex-math></inline-formula> SiPM array is similarly read by an SL for column discrimination. Hence, the detector has only four outputs. We built <inline-formula> <tex-math notation="LaTeX">4\times4 </tex-math></inline-formula> and <inline-formula> <tex-math notation="LaTeX">8\times8 </tex-math></inline-formula> detector modules (DMs) by using 3.0-mm<inline-formula> <tex-math notation="LaTeX">^{3}\,\,\times3.0 </tex-math></inline-formula>-mm<inline-formula> <tex-math notation="LaTeX">^{3}\,\,\times20 </tex-math></inline-formula>-mm3 lutetium-yttrium oxyorthosilicates. The outputs were sampled and processed offline. For both DMs, crystal discrimination was successful. For the 4<inline-formula> <tex-math notation="LaTeX">\times </tex-math></inline-formula>4 DM, we obtained an average energy resolution (ER) of 14.1%, an average DOI resolution of 2.5 mm, a non DOI-corrected coincidence resolving time (CRT), measured in coincidence with a single-pixel reference detector (refDet), of about 495ps. For the 8<inline-formula> <tex-math notation="LaTeX">\times </tex-math></inline-formula>8 DM, the average ER, average DOI resolution and average CRT were 16.4%, 2.9 mm, and 641ps, respectively. We identified the intercrystal scattering as a probable cause for the CRT deterioration when the DM was increased from 4<inline-formula> <tex-math notation="LaTeX">\times </tex-math></inline-formula>4 to 8<inline-formula> <tex-math notation="LaTeX">\times </tex-math></inline-formula>8.]]></abstract><cop>United States</cop><pub>IEEE</pub><pmid>38654812</pmid><doi>10.1109/TRPMS.2024.3360942</doi><tpages>8</tpages><orcidid>https://orcid.org/0000-0002-8229-0720</orcidid><orcidid>https://orcid.org/0000-0001-5353-2201</orcidid><orcidid>https://orcid.org/0009-0000-0900-0216</orcidid><orcidid>https://orcid.org/0000-0002-8785-5225</orcidid><orcidid>https://orcid.org/0000-0003-3372-2803</orcidid></addata></record> |
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subjects | Arrays Back Cathode ray tubes Crystals Depth-of-interaction (DOI) Detectors Energy resolution Histograms Lutetium Multiplexing PET detector Photomultiplier tubes Scintillators Sensors stripline (SL) Time measurement time of flight (TOF) Yttrium |
title | DOI- and TOF-Capable PET Array Detector Using Double-Ended Light Readout and Stripline-Based Row and Column Electronic Readout |
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