Aberrant splicing of Ca V 1.2 calcium channel induced by decreased Rbfox1 enhances arterial constriction during diabetic hyperglycemia

Diabetic hyperglycemia induces dysfunctions of arterial smooth muscle, leading to diabetic vascular complications. The Ca 1.2 calcium channel is one primary pathway for Ca influx, which initiates vasoconstriction. However, the long-term regulation mechanism(s) for vascular Ca 1.2 functions under hyp...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Cellular and molecular life sciences : CMLS 2024-04, Vol.81 (1), p.164
Hauptverfasser:	Hou, Wei, Yin, Shumin, Li, Pengpeng, Zhang, Ludan, Chen, Tiange, Qin, Dongxia, Mustafa, Atta Ul, Liu, Caijie, Song, Miaomiao, Qiu, Cheng, Xiong, Xiaoqing, Wang, Juejin
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium - metabolism Calcium Channels, L-Type - genetics Calcium Channels, L-Type - metabolism Constriction Diabetes Mellitus, Experimental - complications Diabetes Mellitus, Experimental - genetics Diabetes Mellitus, Experimental - metabolism Diabetic Angiopathies - metabolism Glucose - metabolism Hyperglycemia - genetics Hyperglycemia - metabolism Muscle, Smooth, Vascular - metabolism Myocytes, Smooth Muscle - metabolism Rats Rats, Sprague-Dawley
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!