Expression of the Mouse Serum Albumin Gene Introduced into Differentiated and Dedifferentiated Rat Hepatoma Cells

A 23-kilobase-pair segment of DNA containing the entire mouse serum albumin gene as well as 2.2 kilobase pairs of 5′and 4.3 kilobase pairs of 3′flanking sequences has been introduced into pSV2dhfr, a plasmid in which expression of the mouse dihydrofolate reductase cDNA is under the control of simian...

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Veröffentlicht in:	Proceedings of the National Academy of Sciences - PNAS 1985-02, Vol.82 (3), p.765-769
Hauptverfasser:	Deschatrette, Jean, Fougere-Deschatrette, Catherine, Corcos, Laurent, Schimke, Robert T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Albumins Animals Bacteriophages - genetics Biological and medical sciences Cell Differentiation Cell Line Cell lines Cells Cellular differentiation Complementary DNA Drug Resistance Fundamental and applied biological sciences. Psychology Gene expression Gene Expression Regulation Hepatocellular carcinoma Liver Neoplasms, Experimental - drug therapy Liver Neoplasms, Experimental - metabolism Messenger RNA Methotrexate - therapeutic use Molecular and cellular biology Molecular genetics Plasmids Rats RNA, Messenger - analysis Secretion Serum Albumin - genetics Tetrahydrofolate Dehydrogenase - genetics Transfection
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