A novel ultrasensitive chemiluminescence enzyme immunoassay by employment of a signal enhancement of horseradish peroxidase-luminol-hydrogen peroxide reaction for the quantitation of atezolizumab, a monoclonal antibody used for cancer immunotherapy

This study describes, for the first time, the development and validation of a novel ultrasensitive chemiluminescence enzyme immunoassay (CLEIA) for the quantification of atezolizumab (ATZ), a monoclonal antibody approved by the FDA for treatment of different types of cancer. The assay involved the n...

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Veröffentlicht in:RSC advances 2024-03, Vol.14 (12), p.8167-8177
Hauptverfasser: Darwish, Ibrahim A, Ali, Mohammad A. H, Alsalhi, Mohammed S, Zhang, Daohong
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Sprache:eng
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