Evaluating β 2 -agonists as siRNA delivery adjuvants for pulmonary surfactant-coated nanogel inhalation therapy

The lung is an attractive target organ for inhalation of RNA therapeutics, such as small interfering RNA (siRNA). However, clinical translation of siRNA drugs for application in the lung is hampered by many extra- and intracellular barriers. We previously developed hybrid nanoparticles consisting of...

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Veröffentlicht in:	European journal of pharmaceutics and biopharmaceutics 2024-02, p.114223
Hauptverfasser:	Merckx, Pieterjan, Conickx, Griet, Blomme, Evy, Maes, Tania, Bracke, Ken, Brusselle, Guy, De Smedt, Stefaan C, Raemdonck, Koen
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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