Lupus dermal fibroblasts are pro-inflammatory and exhibit a pro-fibrotic phenotype in scarring skin disease

Fibroblasts are stromal cells known to regulate local immune responses important for wound healing and scar formation; however, the cellular mechanisms driving damage and scarring in cutaneous lupus erythematosus (CLE) patients remain poorly understood. Dermal fibroblasts in systemic lupus erythemat...

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Veröffentlicht in:JCI insight 2024-02
Hauptverfasser: Shoffner-Beck, Suzanne K, Abernathy-Close, Lisa, Lazar, Stephanie, Ma, Feiyang, Gharaee-Kermani, Mehrnaz, Hurst, Amy, Dobry, Craig, Pandian, Deepika, Wasikowski, Rachael, Victory, Amanda, Arnold, Kelly, Gudjonsson, Johann E, Tsoi, Lam C, Kahlenberg, J Michelle
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Sprache:eng
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