Biological evaluation of novel side chain containing CQTrICh-analogs as antimalarials and their development as Pf CDPK1 kinase inhibitors

The rapid emergence of resistance to existing frontline antimalarial drugs emphasizes a need for the development of target-oriented molecules with novel modes of action. Given the importance of a plant-like Calcium-Dependent Protein Kinase 1 ( CDPK1) as a stand-alone multistage signalling regulator...

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Veröffentlicht in:	Heliyon 2024-02, Vol.10 (3), p.e25077
Hauptverfasser:	Irfan, Iram, Uddin, Amad, Jain, Ravi, Gupta, Aashima, Gupta, Sonal, Napoleon, John V, Hussain, Afzal, Alajmi, Mohamed F, Joshi, Mukesh C, Hasan, Phool, Kumar, Purnendu, Abid, Mohammad, Singh, Shailja
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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