Apnea Testing Practice to Increase Baseline PaCO 2 and Frequency of Blood Gas Analyses
To study the influence of the initial partial pressure of carbon dioxide (PaCO ) and frequency of blood gas analyses on the positivity rate and safety of apnea testing (AT). A prospective multicenter cohort study. Seven teaching hospitals. A total of 55 patients who underwent AT. Patients were divid...
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| Veröffentlicht in: | Journal of cardiothoracic and vascular anesthesia 2023-12 |
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| container_title | Journal of cardiothoracic and vascular anesthesia |
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| creator | Fan, Linlin Li, Wei Du, Ran Hu, Yajuan Li, Wenchen Zhu, Wenhao Zhang, Lei Su, Yingying |
| description | To study the influence of the initial partial pressure of carbon dioxide (PaCO
) and frequency of blood gas analyses on the positivity rate and safety of apnea testing (AT).
A prospective multicenter cohort study.
Seven teaching hospitals.
A total of 55 patients who underwent AT.
Patients were divided into 2 groups according to their initial PaCO
-the experimental group (≥40 mmHg, 27 patients) and the control group ( |
| doi_str_mv | 10.1053/j.jvca.2023.12.028 |
| format | Article |
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) and frequency of blood gas analyses on the positivity rate and safety of apnea testing (AT).
A prospective multicenter cohort study.
Seven teaching hospitals.
A total of 55 patients who underwent AT.
Patients were divided into 2 groups according to their initial PaCO
-the experimental group (≥40 mmHg, 27 patients) and the control group (<40 mmHg, 28 patients). Blood gas analysis was performed at 3, 5, and 8 minutes, and vital signs were taken. AT results and complications were compared between the groups.
The initial PaCO
of the experimental group was 42.8 ± 2.2 mmHg v 36.4 ± 2.9 mmHg in the controls. The AT positivity rate was 100%. The experimental group needed less time to reach the target PaCO
than the control group (4.07 ± 1.27 minutes v 5.68 ± 2.06 minutes; p = 0.001). Twenty-six patients (96.3%) in the experimental group reached the target PaCO
in 5 minutes v 17 in the control group (60.7%) (p = 0.001). Seven patients (12.7%) were unable to complete 8-minute disconnection due to hypotension. The experimental group had a slightly lower incidence of hypotension than the control group, but there was no statistical difference (7.4% v 17.9%, p = 0.245).
Increasing the baseline PaCO
and doing more blood gas analyses can significantly shorten the time needed for AT and improve the AT positivity rate.</description><identifier>EISSN: 1532-8422</identifier><identifier>DOI: 10.1053/j.jvca.2023.12.028</identifier><identifier>PMID: 38246819</identifier><language>eng</language><publisher>United States</publisher><ispartof>Journal of cardiothoracic and vascular anesthesia, 2023-12</ispartof><rights>Copyright © 2023 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/38246819$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fan, Linlin</creatorcontrib><creatorcontrib>Li, Wei</creatorcontrib><creatorcontrib>Du, Ran</creatorcontrib><creatorcontrib>Hu, Yajuan</creatorcontrib><creatorcontrib>Li, Wenchen</creatorcontrib><creatorcontrib>Zhu, Wenhao</creatorcontrib><creatorcontrib>Zhang, Lei</creatorcontrib><creatorcontrib>Su, Yingying</creatorcontrib><creatorcontrib>Brain Injury Evaluation Quality Control Center of National Health Commission</creatorcontrib><title>Apnea Testing Practice to Increase Baseline PaCO 2 and Frequency of Blood Gas Analyses</title><title>Journal of cardiothoracic and vascular anesthesia</title><addtitle>J Cardiothorac Vasc Anesth</addtitle><description>To study the influence of the initial partial pressure of carbon dioxide (PaCO
) and frequency of blood gas analyses on the positivity rate and safety of apnea testing (AT).
A prospective multicenter cohort study.
Seven teaching hospitals.
A total of 55 patients who underwent AT.
Patients were divided into 2 groups according to their initial PaCO
-the experimental group (≥40 mmHg, 27 patients) and the control group (<40 mmHg, 28 patients). Blood gas analysis was performed at 3, 5, and 8 minutes, and vital signs were taken. AT results and complications were compared between the groups.
The initial PaCO
of the experimental group was 42.8 ± 2.2 mmHg v 36.4 ± 2.9 mmHg in the controls. The AT positivity rate was 100%. The experimental group needed less time to reach the target PaCO
than the control group (4.07 ± 1.27 minutes v 5.68 ± 2.06 minutes; p = 0.001). Twenty-six patients (96.3%) in the experimental group reached the target PaCO
in 5 minutes v 17 in the control group (60.7%) (p = 0.001). Seven patients (12.7%) were unable to complete 8-minute disconnection due to hypotension. The experimental group had a slightly lower incidence of hypotension than the control group, but there was no statistical difference (7.4% v 17.9%, p = 0.245).
Increasing the baseline PaCO
and doing more blood gas analyses can significantly shorten the time needed for AT and improve the AT positivity rate.</description><issn>1532-8422</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><recordid>eNqFjruOwjAQAC0kdLzuByhO-wP47HUCuRIQj6ugQLTRnrOcEgUn2AEpfw8F1DQzzRQjxFgrqVVsvgtZ3CxJVGikRqkw6Yi-jg1OkgixJwYhFEppHcezD9EzCUbTRP_0xXFeOyY4cGhy9w97T7bJLUNTwa-znikwLB4oc8ewp-UOEMhlsPZ8ubKzLVQnWJRVlcGGAswdlW3gMBLdE5WBP58eiq_16rDcTurr35mztPb5mXybvkbM2-AO0MJDAg</recordid><startdate>20231221</startdate><enddate>20231221</enddate><creator>Fan, Linlin</creator><creator>Li, Wei</creator><creator>Du, Ran</creator><creator>Hu, Yajuan</creator><creator>Li, Wenchen</creator><creator>Zhu, Wenhao</creator><creator>Zhang, Lei</creator><creator>Su, Yingying</creator><scope>NPM</scope></search><sort><creationdate>20231221</creationdate><title>Apnea Testing Practice to Increase Baseline PaCO 2 and Frequency of Blood Gas Analyses</title><author>Fan, Linlin ; Li, Wei ; Du, Ran ; Hu, Yajuan ; Li, Wenchen ; Zhu, Wenhao ; Zhang, Lei ; Su, Yingying</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-pubmed_primary_382468193</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fan, Linlin</creatorcontrib><creatorcontrib>Li, Wei</creatorcontrib><creatorcontrib>Du, Ran</creatorcontrib><creatorcontrib>Hu, Yajuan</creatorcontrib><creatorcontrib>Li, Wenchen</creatorcontrib><creatorcontrib>Zhu, Wenhao</creatorcontrib><creatorcontrib>Zhang, Lei</creatorcontrib><creatorcontrib>Su, Yingying</creatorcontrib><creatorcontrib>Brain Injury Evaluation Quality Control Center of National Health Commission</creatorcontrib><collection>PubMed</collection><jtitle>Journal of cardiothoracic and vascular anesthesia</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Fan, Linlin</au><au>Li, Wei</au><au>Du, Ran</au><au>Hu, Yajuan</au><au>Li, Wenchen</au><au>Zhu, Wenhao</au><au>Zhang, Lei</au><au>Su, Yingying</au><aucorp>Brain Injury Evaluation Quality Control Center of National Health Commission</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Apnea Testing Practice to Increase Baseline PaCO 2 and Frequency of Blood Gas Analyses</atitle><jtitle>Journal of cardiothoracic and vascular anesthesia</jtitle><addtitle>J Cardiothorac Vasc Anesth</addtitle><date>2023-12-21</date><risdate>2023</risdate><eissn>1532-8422</eissn><abstract>To study the influence of the initial partial pressure of carbon dioxide (PaCO
) and frequency of blood gas analyses on the positivity rate and safety of apnea testing (AT).
A prospective multicenter cohort study.
Seven teaching hospitals.
A total of 55 patients who underwent AT.
Patients were divided into 2 groups according to their initial PaCO
-the experimental group (≥40 mmHg, 27 patients) and the control group (<40 mmHg, 28 patients). Blood gas analysis was performed at 3, 5, and 8 minutes, and vital signs were taken. AT results and complications were compared between the groups.
The initial PaCO
of the experimental group was 42.8 ± 2.2 mmHg v 36.4 ± 2.9 mmHg in the controls. The AT positivity rate was 100%. The experimental group needed less time to reach the target PaCO
than the control group (4.07 ± 1.27 minutes v 5.68 ± 2.06 minutes; p = 0.001). Twenty-six patients (96.3%) in the experimental group reached the target PaCO
in 5 minutes v 17 in the control group (60.7%) (p = 0.001). Seven patients (12.7%) were unable to complete 8-minute disconnection due to hypotension. The experimental group had a slightly lower incidence of hypotension than the control group, but there was no statistical difference (7.4% v 17.9%, p = 0.245).
Increasing the baseline PaCO
and doing more blood gas analyses can significantly shorten the time needed for AT and improve the AT positivity rate.</abstract><cop>United States</cop><pmid>38246819</pmid><doi>10.1053/j.jvca.2023.12.028</doi></addata></record> |
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| ispartof | Journal of cardiothoracic and vascular anesthesia, 2023-12 |
| issn | 1532-8422 |
| language | eng |
| recordid | cdi_pubmed_primary_38246819 |
| source | Elsevier ScienceDirect Journals |
| title | Apnea Testing Practice to Increase Baseline PaCO 2 and Frequency of Blood Gas Analyses |
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