Vitamin B 12 produced by gut bacteria modulates cholinergic signalling

A growing body of evidence indicates that gut microbiota influence brain function and behaviour. However, the molecular basis of how gut bacteria modulate host nervous system function is largely unknown. Here we show that vitamin B -producing bacteria that colonize the intestine can modulate excitat...

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Veröffentlicht in:	Nature cell biology 2024-01, Vol.26 (1), p.72
Hauptverfasser:	Kang, Woo Kyu, Florman, Jeremy T, Araya, Antonia, Fox, Bennett W, Thackeray, Andrea, Schroeder, Frank C, Walhout, Albertha J M, Alkema, Mark J
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Bacteria - metabolism Caenorhabditis elegans - metabolism Choline - metabolism Cholinergic Agents - metabolism Methionine - metabolism S-Adenosylmethionine - metabolism Vitamin B 12 - metabolism Vitamins - metabolism
Online-Zugang:	Volltext
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