Targeted Alpha Therapy: All We Need to Know about 225 Ac's Physical Characteristics and Production as a Potential Theranostic Radionuclide

The high energy of α emitters, and the strong linear energy transfer that goes along with it, lead to very efficient cell killing through DNA damage. Moreover, the degree of oxygenation and the cell cycle state have no impact on these effects. Therefore, α radioisotopes can offer a treatment choice...

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Veröffentlicht in:Pharmaceuticals (Basel, Switzerland) Switzerland), 2023-12, Vol.16 (12)
Hauptverfasser: Jalloul, Wael, Ghizdovat, Vlad, Stolniceanu, Cati Raluca, Ionescu, Teodor, Grierosu, Irena Cristina, Pavaleanu, Ioana, Moscalu, Mihaela, Stefanescu, Cipriana
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Sprache:eng
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