Super-enhancer RNA m 6 A promotes local chromatin accessibility and oncogene transcription in pancreatic ductal adenocarcinoma

The biological functions of noncoding RNA N -methyladenosine (m A) modification remain poorly understood. In the present study, we depict the landscape of super-enhancer RNA (seRNA) m A modification in pancreatic ductal adenocarcinoma (PDAC) and reveal a regulatory axis of m A seRNA, H3K4me3 modific...

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Veröffentlicht in:	Nature genetics 2023-12, Vol.55 (12), p.2224
Hauptverfasser:	Li, Rui, Zhao, Hongzhe, Huang, Xudong, Zhang, Jialiang, Bai, Ruihong, Zhuang, Lisha, Wen, Shujuan, Wu, Shaojia, Zhou, Quanbo, Li, Mei, Zeng, Lingxing, Zhang, Shaoping, Deng, Shuang, Su, Jiachun, Zuo, Zhixiang, Chen, Rufu, Lin, Dongxin, Zheng, Jian
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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