G Protein-Coupled Receptor Kinase 2 Selectively Enhances β-Arrestin Recruitment to the D 2 Dopamine Receptor through Mechanisms That Are Independent of Receptor Phosphorylation

The D2 dopamine receptor (D2R) signals through both G proteins and β-arrestins to regulate important physiological processes, such as movement, reward circuitry, emotion, and cognition. β-arrestins are believed to interact with G protein-coupled receptors (GPCRs) at the phosphorylated C-terminal tai...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biomolecules (Basel, Switzerland) Switzerland), 2023-10, Vol.13 (10)
Hauptverfasser:	Sánchez-Soto, Marta, Boldizsar, Noelia M, Schardien, Kayla A, Madaras, Nora S, Willette, Blair K A, Inbody, Laura R, Dasaro, Christopher, Moritz, Amy E, Drube, Julia, Haider, Raphael S, Free, R Benjamin, Hoffman, Carsten, Sibley, David R
Format:	Artikel
Sprache:	eng
Schlagworte:	Arrestins - metabolism beta-Arrestins - metabolism G-Protein-Coupled Receptor Kinases - metabolism HEK293 Cells Humans Phosphorylation Protein Isoforms - metabolism Receptors, Dopamine - metabolism Receptors, G-Protein-Coupled - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!