The Role of Intracellular Ca 2+ and Mitochondrial ROS in Small Aβ 1-42 Oligomer-Induced Microglial Death

Alzheimer's disease (AD) is the most common form of dementia worldwide, and it contributes up to 70% of cases. AD pathology involves abnormal amyloid beta (Aβ) accumulation, and the link between the Aβ structure and toxicity is of major interest. NMDA receptors (NMDAR) are thought to be essenti...

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Veröffentlicht in:International journal of molecular sciences 2023-08, Vol.24 (15)
Hauptverfasser: Jekabsone, Aiste, Jankeviciute, Silvija, Pampuscenko, Katryna, Borutaite, Vilmante, Morkuniene, Ramune
Format: Artikel
Sprache:eng
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