Avitene granulomas of colonic serosa
Avitene, microfibrillar collagen hemostat, is an absorbable topical hemostatic agent prepared from purified bovine corium collagen. A case is reported of a 58-year-old man who, one month after sigmoid colectomy for volvulus in which Avitene as used to control bleeding from a splenic capsular tear, d...
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| Veröffentlicht in: | Annals of clinical and laboratory science 1986-07, Vol.16 (4), p.296-302 |
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| container_title | Annals of clinical and laboratory science |
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| creator | MCGREGOR, D. H MACARTHUR, R. I CARTER, T |
| description | Avitene, microfibrillar collagen hemostat, is an absorbable topical hemostatic agent prepared from purified bovine corium collagen. A case is reported of a 58-year-old man who, one month after sigmoid colectomy for volvulus in which Avitene as used to control bleeding from a splenic capsular tear, developed symptoms of intestinal obstruction. On exploratory laparotomy, the transverse and descending colon had numerous 0.1 to 2.0 cm nodules, adherent to the serosa of the bowel and mesentery, with kinking and partial obstruction of the splenic flexure. Light microscopically, the nodules were found to be composed of chronic inflammatory and granulomatous reaction with numerous deposits of eosinophilic fibrillar material consistent with Avitene. Electron microscopic examination of the lesions and of Avitene confirmed the nature of this material. The practical and pathobiological implications of utilization of Avitene as a hemostatic agent are discussed. |
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I ; CARTER, T</creator><creatorcontrib>MCGREGOR, D. H ; MACARTHUR, R. I ; CARTER, T</creatorcontrib><description>Avitene, microfibrillar collagen hemostat, is an absorbable topical hemostatic agent prepared from purified bovine corium collagen. A case is reported of a 58-year-old man who, one month after sigmoid colectomy for volvulus in which Avitene as used to control bleeding from a splenic capsular tear, developed symptoms of intestinal obstruction. On exploratory laparotomy, the transverse and descending colon had numerous 0.1 to 2.0 cm nodules, adherent to the serosa of the bowel and mesentery, with kinking and partial obstruction of the splenic flexure. Light microscopically, the nodules were found to be composed of chronic inflammatory and granulomatous reaction with numerous deposits of eosinophilic fibrillar material consistent with Avitene. Electron microscopic examination of the lesions and of Avitene confirmed the nature of this material. The practical and pathobiological implications of utilization of Avitene as a hemostatic agent are discussed.</description><identifier>ISSN: 0091-7370</identifier><identifier>EISSN: 1550-8080</identifier><identifier>PMID: 3740798</identifier><identifier>CODEN: ACLSCP</identifier><language>eng</language><publisher>Philadelphia, PA: Institute for Clinical Science</publisher><subject>Adipose Tissue - pathology ; Biological and medical sciences ; Collagen - adverse effects ; Collagen - metabolism ; Colonic Diseases - chemically induced ; Colonic Diseases - pathology ; Drug toxicity and drugs side effects treatment ; Granuloma - chemically induced ; Granuloma - pathology ; Histiocytes - pathology ; Histocytochemistry ; Humans ; Male ; Medical sciences ; Microscopy, Electron ; Middle Aged ; Pharmacology. 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I</creatorcontrib><creatorcontrib>CARTER, T</creatorcontrib><title>Avitene granulomas of colonic serosa</title><title>Annals of clinical and laboratory science</title><addtitle>Ann Clin Lab Sci</addtitle><description>Avitene, microfibrillar collagen hemostat, is an absorbable topical hemostatic agent prepared from purified bovine corium collagen. A case is reported of a 58-year-old man who, one month after sigmoid colectomy for volvulus in which Avitene as used to control bleeding from a splenic capsular tear, developed symptoms of intestinal obstruction. On exploratory laparotomy, the transverse and descending colon had numerous 0.1 to 2.0 cm nodules, adherent to the serosa of the bowel and mesentery, with kinking and partial obstruction of the splenic flexure. Light microscopically, the nodules were found to be composed of chronic inflammatory and granulomatous reaction with numerous deposits of eosinophilic fibrillar material consistent with Avitene. Electron microscopic examination of the lesions and of Avitene confirmed the nature of this material. The practical and pathobiological implications of utilization of Avitene as a hemostatic agent are discussed.</description><subject>Adipose Tissue - pathology</subject><subject>Biological and medical sciences</subject><subject>Collagen - adverse effects</subject><subject>Collagen - metabolism</subject><subject>Colonic Diseases - chemically induced</subject><subject>Colonic Diseases - pathology</subject><subject>Drug toxicity and drugs side effects treatment</subject><subject>Granuloma - chemically induced</subject><subject>Granuloma - pathology</subject><subject>Histiocytes - pathology</subject><subject>Histocytochemistry</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Microscopy, Electron</subject><subject>Middle Aged</subject><subject>Pharmacology. Drug treatments</subject><subject>Serous Membrane - pathology</subject><subject>Toxicity: digestive system</subject><issn>0091-7370</issn><issn>1550-8080</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1986</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9jstqwzAUREVpSZ20n1DwIlvDlfX0MoQ-AoFumnW4kq6Ki20ZKyn072uo6WoWZ5g5N6zgSkFlwcItKwAaXhlh4J6tc_4CqBspYcVWwkgwjS3YdvfdXmig8nPC4dqlHnOZYulTl4bWl5mmlPGB3UXsMj0uuWGnl-eP_Vt1fH897HfHaqyFulTcOqm1I6ecACIVayFQg4qGh_lONRgFlxwVkZHCawBrKHAXMCjrvRUb9vS3O15dT-E8Tm2P0895sZ35duGYPXZxVvZt_q9ZMFxqKX4BPoJH9Q</recordid><startdate>19860701</startdate><enddate>19860701</enddate><creator>MCGREGOR, D. H</creator><creator>MACARTHUR, R. I</creator><creator>CARTER, T</creator><general>Institute for Clinical Science</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>19860701</creationdate><title>Avitene granulomas of colonic serosa</title><author>MCGREGOR, D. H ; MACARTHUR, R. I ; CARTER, T</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p235t-18b466beb5b30ee5f233a605f71d40759af3141a5ee743c60087ed1bdad58cc83</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1986</creationdate><topic>Adipose Tissue - pathology</topic><topic>Biological and medical sciences</topic><topic>Collagen - adverse effects</topic><topic>Collagen - metabolism</topic><topic>Colonic Diseases - chemically induced</topic><topic>Colonic Diseases - pathology</topic><topic>Drug toxicity and drugs side effects treatment</topic><topic>Granuloma - chemically induced</topic><topic>Granuloma - pathology</topic><topic>Histiocytes - pathology</topic><topic>Histocytochemistry</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Microscopy, Electron</topic><topic>Middle Aged</topic><topic>Pharmacology. Drug treatments</topic><topic>Serous Membrane - pathology</topic><topic>Toxicity: digestive system</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>MCGREGOR, D. H</creatorcontrib><creatorcontrib>MACARTHUR, R. I</creatorcontrib><creatorcontrib>CARTER, T</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Annals of clinical and laboratory science</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>MCGREGOR, D. H</au><au>MACARTHUR, R. I</au><au>CARTER, T</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Avitene granulomas of colonic serosa</atitle><jtitle>Annals of clinical and laboratory science</jtitle><addtitle>Ann Clin Lab Sci</addtitle><date>1986-07-01</date><risdate>1986</risdate><volume>16</volume><issue>4</issue><spage>296</spage><epage>302</epage><pages>296-302</pages><issn>0091-7370</issn><eissn>1550-8080</eissn><coden>ACLSCP</coden><abstract>Avitene, microfibrillar collagen hemostat, is an absorbable topical hemostatic agent prepared from purified bovine corium collagen. A case is reported of a 58-year-old man who, one month after sigmoid colectomy for volvulus in which Avitene as used to control bleeding from a splenic capsular tear, developed symptoms of intestinal obstruction. On exploratory laparotomy, the transverse and descending colon had numerous 0.1 to 2.0 cm nodules, adherent to the serosa of the bowel and mesentery, with kinking and partial obstruction of the splenic flexure. Light microscopically, the nodules were found to be composed of chronic inflammatory and granulomatous reaction with numerous deposits of eosinophilic fibrillar material consistent with Avitene. Electron microscopic examination of the lesions and of Avitene confirmed the nature of this material. The practical and pathobiological implications of utilization of Avitene as a hemostatic agent are discussed.</abstract><cop>Philadelphia, PA</cop><pub>Institute for Clinical Science</pub><pmid>3740798</pmid><tpages>7</tpages></addata></record> |
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| identifier | ISSN: 0091-7370 |
| ispartof | Annals of clinical and laboratory science, 1986-07, Vol.16 (4), p.296-302 |
| issn | 0091-7370 1550-8080 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals |
| subjects | Adipose Tissue - pathology Biological and medical sciences Collagen - adverse effects Collagen - metabolism Colonic Diseases - chemically induced Colonic Diseases - pathology Drug toxicity and drugs side effects treatment Granuloma - chemically induced Granuloma - pathology Histiocytes - pathology Histocytochemistry Humans Male Medical sciences Microscopy, Electron Middle Aged Pharmacology. Drug treatments Serous Membrane - pathology Toxicity: digestive system |
| title | Avitene granulomas of colonic serosa |
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