Synthesis, reactions and application of chalcones: a systematic review

Chalcones are a group of naturally occurring compounds that have biological effects that include anti-inflammatory, anti-cancer, and antibacterial properties. Current chalcone research, including their synthesis, structure-activity relationships, and biological activities, is summarized herein. Alon...

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Veröffentlicht in:Organic & biomolecular chemistry 2023-07, Vol.21 (26), p.5317-5346
Hauptverfasser: Shalaby, Mona A, Rizk, Sameh A, Fahim, Asmaa M
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creator Shalaby, Mona A
Rizk, Sameh A
Fahim, Asmaa M
description Chalcones are a group of naturally occurring compounds that have biological effects that include anti-inflammatory, anti-cancer, and antibacterial properties. Current chalcone research, including their synthesis, structure-activity relationships, and biological activities, is summarized herein. Along with their toxicity and safety profiles, the prospective usage of chalcones in medicinal research and development is discussed. This review emphasizes the need for additional research in order to fully examine the therapeutic potential of chalcones as therapeutic agents for the treatment of a variety of disorders. Chalcones, Reactions, Synthesis, Biological activity, Industrial application.
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subjects Anti-Bacterial Agents - pharmacology
Anticancer properties
Antineoplastic Agents - pharmacology
Biological activity
Biological effects
Chalcone
Chalcones - pharmacology
Chemical synthesis
Inflammation
Pharmacology
Prospective Studies
R&D
Research & development
Structure-Activity Relationship
Toxicity
title Synthesis, reactions and application of chalcones: a systematic review
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