Synthesis, reactions and application of chalcones: a systematic review
Chalcones are a group of naturally occurring compounds that have biological effects that include anti-inflammatory, anti-cancer, and antibacterial properties. Current chalcone research, including their synthesis, structure-activity relationships, and biological activities, is summarized herein. Alon...
Gespeichert in:
Veröffentlicht in: | Organic & biomolecular chemistry 2023-07, Vol.21 (26), p.5317-5346 |
---|---|
Hauptverfasser: | , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 5346 |
---|---|
container_issue | 26 |
container_start_page | 5317 |
container_title | Organic & biomolecular chemistry |
container_volume | 21 |
creator | Shalaby, Mona A Rizk, Sameh A Fahim, Asmaa M |
description | Chalcones are a group of naturally occurring compounds that have biological effects that include anti-inflammatory, anti-cancer, and antibacterial properties. Current chalcone research, including their synthesis, structure-activity relationships, and biological activities, is summarized herein. Along with their toxicity and safety profiles, the prospective usage of chalcones in medicinal research and development is discussed. This review emphasizes the need for additional research in order to fully examine the therapeutic potential of chalcones as therapeutic agents for the treatment of a variety of disorders.
Chalcones, Reactions, Synthesis, Biological activity, Industrial application. |
doi_str_mv | 10.1039/d3ob00792h |
format | Article |
fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmed_primary_37338020</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2833007539</sourcerecordid><originalsourceid>FETCH-LOGICAL-c337t-94c11b76ec8e9a545010b463545ef425e21a6fc0cdb864a769d2e6a026be7fc53</originalsourceid><addsrcrecordid>eNpdkc9LwzAUx4Mobk4v3pWCFxGr-dWk9abTOWGwg3ouafrKOtqmJq2y_97MzQkeQh7vffLl8QlCpwTfEMyS25yZDGOZ0MUeGhIuZYgjluzvaooH6Mi5JcYkkYIfogGTjMWY4iGavK6abgGudNeBBaW70jQuUE0eqLatSq3WjcAUgV6oSpsG3F2gArdyHdR-pv2jzxK-jtFBoSoHJ9t7hN4nT2_jaTibP7-M72ehZkx2YcI1IZkUoGNIVMQjTHDGBfMVFJxGQIkShcY6z2LBlRRJTkEoTEUGstARG6HLTW5rzUcPrkvr0mmoKtWA6V1KY-o9MO7PCF38Q5emt43fzlOMeWFekqeuNpS2xjkLRdraslZ2lRKcru2mj2z-8GN36uHzbWSf1ZDv0F-dHjjbANbp3fTve9g30lB9gQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2833007539</pqid></control><display><type>article</type><title>Synthesis, reactions and application of chalcones: a systematic review</title><source>MEDLINE</source><source>Royal Society Of Chemistry Journals</source><source>Alma/SFX Local Collection</source><creator>Shalaby, Mona A ; Rizk, Sameh A ; Fahim, Asmaa M</creator><creatorcontrib>Shalaby, Mona A ; Rizk, Sameh A ; Fahim, Asmaa M</creatorcontrib><description>Chalcones are a group of naturally occurring compounds that have biological effects that include anti-inflammatory, anti-cancer, and antibacterial properties. Current chalcone research, including their synthesis, structure-activity relationships, and biological activities, is summarized herein. Along with their toxicity and safety profiles, the prospective usage of chalcones in medicinal research and development is discussed. This review emphasizes the need for additional research in order to fully examine the therapeutic potential of chalcones as therapeutic agents for the treatment of a variety of disorders.
Chalcones, Reactions, Synthesis, Biological activity, Industrial application.</description><identifier>ISSN: 1477-0520</identifier><identifier>EISSN: 1477-0539</identifier><identifier>DOI: 10.1039/d3ob00792h</identifier><identifier>PMID: 37338020</identifier><language>eng</language><publisher>England: Royal Society of Chemistry</publisher><subject>Anti-Bacterial Agents - pharmacology ; Anticancer properties ; Antineoplastic Agents - pharmacology ; Biological activity ; Biological effects ; Chalcone ; Chalcones - pharmacology ; Chemical synthesis ; Inflammation ; Pharmacology ; Prospective Studies ; R&D ; Research & development ; Structure-Activity Relationship ; Toxicity</subject><ispartof>Organic & biomolecular chemistry, 2023-07, Vol.21 (26), p.5317-5346</ispartof><rights>Copyright Royal Society of Chemistry 2023</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c337t-94c11b76ec8e9a545010b463545ef425e21a6fc0cdb864a769d2e6a026be7fc53</citedby><cites>FETCH-LOGICAL-c337t-94c11b76ec8e9a545010b463545ef425e21a6fc0cdb864a769d2e6a026be7fc53</cites><orcidid>0000-0002-8232-5399 ; 0000-0002-0293-3491</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37338020$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Shalaby, Mona A</creatorcontrib><creatorcontrib>Rizk, Sameh A</creatorcontrib><creatorcontrib>Fahim, Asmaa M</creatorcontrib><title>Synthesis, reactions and application of chalcones: a systematic review</title><title>Organic & biomolecular chemistry</title><addtitle>Org Biomol Chem</addtitle><description>Chalcones are a group of naturally occurring compounds that have biological effects that include anti-inflammatory, anti-cancer, and antibacterial properties. Current chalcone research, including their synthesis, structure-activity relationships, and biological activities, is summarized herein. Along with their toxicity and safety profiles, the prospective usage of chalcones in medicinal research and development is discussed. This review emphasizes the need for additional research in order to fully examine the therapeutic potential of chalcones as therapeutic agents for the treatment of a variety of disorders.
Chalcones, Reactions, Synthesis, Biological activity, Industrial application.</description><subject>Anti-Bacterial Agents - pharmacology</subject><subject>Anticancer properties</subject><subject>Antineoplastic Agents - pharmacology</subject><subject>Biological activity</subject><subject>Biological effects</subject><subject>Chalcone</subject><subject>Chalcones - pharmacology</subject><subject>Chemical synthesis</subject><subject>Inflammation</subject><subject>Pharmacology</subject><subject>Prospective Studies</subject><subject>R&D</subject><subject>Research & development</subject><subject>Structure-Activity Relationship</subject><subject>Toxicity</subject><issn>1477-0520</issn><issn>1477-0539</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkc9LwzAUx4Mobk4v3pWCFxGr-dWk9abTOWGwg3ouafrKOtqmJq2y_97MzQkeQh7vffLl8QlCpwTfEMyS25yZDGOZ0MUeGhIuZYgjluzvaooH6Mi5JcYkkYIfogGTjMWY4iGavK6abgGudNeBBaW70jQuUE0eqLatSq3WjcAUgV6oSpsG3F2gArdyHdR-pv2jzxK-jtFBoSoHJ9t7hN4nT2_jaTibP7-M72ehZkx2YcI1IZkUoGNIVMQjTHDGBfMVFJxGQIkShcY6z2LBlRRJTkEoTEUGstARG6HLTW5rzUcPrkvr0mmoKtWA6V1KY-o9MO7PCF38Q5emt43fzlOMeWFekqeuNpS2xjkLRdraslZ2lRKcru2mj2z-8GN36uHzbWSf1ZDv0F-dHjjbANbp3fTve9g30lB9gQ</recordid><startdate>20230705</startdate><enddate>20230705</enddate><creator>Shalaby, Mona A</creator><creator>Rizk, Sameh A</creator><creator>Fahim, Asmaa M</creator><general>Royal Society of Chemistry</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QO</scope><scope>7T7</scope><scope>7TM</scope><scope>8FD</scope><scope>C1K</scope><scope>FR3</scope><scope>P64</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0002-8232-5399</orcidid><orcidid>https://orcid.org/0000-0002-0293-3491</orcidid></search><sort><creationdate>20230705</creationdate><title>Synthesis, reactions and application of chalcones: a systematic review</title><author>Shalaby, Mona A ; Rizk, Sameh A ; Fahim, Asmaa M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c337t-94c11b76ec8e9a545010b463545ef425e21a6fc0cdb864a769d2e6a026be7fc53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Anti-Bacterial Agents - pharmacology</topic><topic>Anticancer properties</topic><topic>Antineoplastic Agents - pharmacology</topic><topic>Biological activity</topic><topic>Biological effects</topic><topic>Chalcone</topic><topic>Chalcones - pharmacology</topic><topic>Chemical synthesis</topic><topic>Inflammation</topic><topic>Pharmacology</topic><topic>Prospective Studies</topic><topic>R&D</topic><topic>Research & development</topic><topic>Structure-Activity Relationship</topic><topic>Toxicity</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Shalaby, Mona A</creatorcontrib><creatorcontrib>Rizk, Sameh A</creatorcontrib><creatorcontrib>Fahim, Asmaa M</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Biotechnology Research Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Nucleic Acids Abstracts</collection><collection>Technology Research Database</collection><collection>Environmental Sciences and Pollution Management</collection><collection>Engineering Research Database</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Organic & biomolecular chemistry</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Shalaby, Mona A</au><au>Rizk, Sameh A</au><au>Fahim, Asmaa M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Synthesis, reactions and application of chalcones: a systematic review</atitle><jtitle>Organic & biomolecular chemistry</jtitle><addtitle>Org Biomol Chem</addtitle><date>2023-07-05</date><risdate>2023</risdate><volume>21</volume><issue>26</issue><spage>5317</spage><epage>5346</epage><pages>5317-5346</pages><issn>1477-0520</issn><eissn>1477-0539</eissn><abstract>Chalcones are a group of naturally occurring compounds that have biological effects that include anti-inflammatory, anti-cancer, and antibacterial properties. Current chalcone research, including their synthesis, structure-activity relationships, and biological activities, is summarized herein. Along with their toxicity and safety profiles, the prospective usage of chalcones in medicinal research and development is discussed. This review emphasizes the need for additional research in order to fully examine the therapeutic potential of chalcones as therapeutic agents for the treatment of a variety of disorders.
Chalcones, Reactions, Synthesis, Biological activity, Industrial application.</abstract><cop>England</cop><pub>Royal Society of Chemistry</pub><pmid>37338020</pmid><doi>10.1039/d3ob00792h</doi><tpages>3</tpages><orcidid>https://orcid.org/0000-0002-8232-5399</orcidid><orcidid>https://orcid.org/0000-0002-0293-3491</orcidid></addata></record> |
fulltext | fulltext |
identifier | ISSN: 1477-0520 |
ispartof | Organic & biomolecular chemistry, 2023-07, Vol.21 (26), p.5317-5346 |
issn | 1477-0520 1477-0539 |
language | eng |
recordid | cdi_pubmed_primary_37338020 |
source | MEDLINE; Royal Society Of Chemistry Journals; Alma/SFX Local Collection |
subjects | Anti-Bacterial Agents - pharmacology Anticancer properties Antineoplastic Agents - pharmacology Biological activity Biological effects Chalcone Chalcones - pharmacology Chemical synthesis Inflammation Pharmacology Prospective Studies R&D Research & development Structure-Activity Relationship Toxicity |
title | Synthesis, reactions and application of chalcones: a systematic review |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T12%3A52%3A35IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Synthesis,%20reactions%20and%20application%20of%20chalcones:%20a%20systematic%20review&rft.jtitle=Organic%20&%20biomolecular%20chemistry&rft.au=Shalaby,%20Mona%20A&rft.date=2023-07-05&rft.volume=21&rft.issue=26&rft.spage=5317&rft.epage=5346&rft.pages=5317-5346&rft.issn=1477-0520&rft.eissn=1477-0539&rft_id=info:doi/10.1039/d3ob00792h&rft_dat=%3Cproquest_pubme%3E2833007539%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2833007539&rft_id=info:pmid/37338020&rfr_iscdi=true |