Aberrant expression of T cell activation markers and upregulation of Tregs in bone marrow and peripheral blood in acute myeloid leukemia patients

T cells' function and activation and the immunosuppressive effect of regulatory T cells (Tregs) play a pivotal role in the occurrence and progression of acute myeloid leukemia (AML). In this study, we investigate the expression of T cell activation markers and quantity of Tregs in bone marrow (...

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Veröffentlicht in:	Hematology (Luxembourg) 2023-12, Vol.28 (1), p.2219554-2219554
Hauptverfasser:	Fang, Junyue, Zhang, Ruihao, Lin, Xianghua, Xu, Ying, Huang, Kezhi, Saw, Phei Er
Format:	Artikel
Sprache:	eng
Schlagworte:	AML bone marrow Bone Marrow - pathology CD8-Positive T-Lymphocytes - pathology HLA-DR Antigens - metabolism Humans Leukemia, Myeloid, Acute - pathology peripheral blood T cell activation markers Tregs Up-Regulation
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