Deficiency in HHT-associated Endoglin elicits hypoxia-driven congestive heart failure in zebrafish

Hereditary hemorrhagic Telangiectasia (HHT) is a rare genetic disease caused by mutations affecting components of Bone Morphogenetic Protein and Transforming Growth Factor-β (BMP/TGF-β) signaling in endothelial cells. This disorder is characterized by arterio-venous malformations which are prone to...

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Veröffentlicht in:	Disease models & mechanisms 2023-05
Hauptverfasser:	Lelièvre, Etienne, Bureau, Charlotte, Bordat, Yann, Frétaud, Maxence, Langevin, Christelle, Jopling, Chris, Kissa, Karima
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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