Transfer function approach to understanding periodic forcing of signal transduction networks

Signal transduction networks are responsible for transferring biochemical signals from the extracellular to the intracellular environment. Understanding the dynamics of these networks helps understand their biological processes. Signals are often delivered in pulses and oscillations. Therefore, unde...

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Veröffentlicht in:	Physical biology 2023-05, Vol.20 (3), p.35001
Hauptverfasser:	Tran, Nguyen H N, Clayton, Andrew H A
Format:	Artikel
Sprache:	eng
Schlagworte:	frequency domain Models, Biological network motifs periodic forcing Signal Transduction - physiology signal transduction networks transfer function
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description	Signal transduction networks are responsible for transferring biochemical signals from the extracellular to the intracellular environment. Understanding the dynamics of these networks helps understand their biological processes. Signals are often delivered in pulses and oscillations. Therefore, understanding the dynamics of these networks under pulsatile and periodic stimuli is useful. One tool to do this is the transfer function. This tutorial outlines the basic theory behind the transfer function approach and walks through some examples of simple signal transduction networks.
doi_str_mv	10.1088/1478-3975/acc300
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subjects	frequency domain Models, Biological network motifs periodic forcing Signal Transduction - physiology signal transduction networks transfer function
title	Transfer function approach to understanding periodic forcing of signal transduction networks
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