The N6-methyladenosine writer WTAP contributes to the induction of immune tolerance post kidney transplantation by targeting regulatory T cells

N6-methyladenosine (m6A) modification is involved in diverse immunoregulation, while the relationship between m6A modification and immune tolerance post kidney transplantation remains unclear. Expression of Wilms tumor 1-associating protein (WTAP), an m6A writer, was firstly detected in tolerant kid...

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Veröffentlicht in:	Laboratory investigation 2022-11, Vol.102 (11), p.1268
Hauptverfasser:	Wang, Zhigang, Qi, Yuanbo, Feng, Yonghua, Xu, Hongen, Wang, Junxiang, Zhang, Luyu, Zhang, Jie, Hou, Xinyue, Feng, Guiwen, Shang, Wenjun
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Cycle Proteins - metabolism Humans Immune Tolerance Kidney Transplantation Mice RNA Splicing Factors - metabolism T-Lymphocytes, Regulatory
Online-Zugang:	Volltext
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