Fractional CO 2 Laser versus Fractional Radiofrequency for Skin Striae Treatment: Study Protocol for a Randomized Controlled Trial

Striae are common dermal lesions associated with physiological and psychological alterations, affecting the quality of life. This proposed randomized controlled trial protocol will evaluate the clinical efficacy and treatment safety of fractional CO laser versus fractional radiofrequency (FRF) in cl...

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Veröffentlicht in:Healthcare (Basel) 2022-11, Vol.10 (12)
Hauptverfasser: Mendes, Nuno, Alves, Paulo Jorge, Barros, Mafalda, Machado, Jorge
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creator Mendes, Nuno
Alves, Paulo Jorge
Barros, Mafalda
Machado, Jorge
description Striae are common dermal lesions associated with physiological and psychological alterations, affecting the quality of life. This proposed randomized controlled trial protocol will evaluate the clinical efficacy and treatment safety of fractional CO laser versus fractional radiofrequency (FRF) in clinical trials. We will randomly allocate 60 subjects who present abdominal striae into two different groups for the treatment, which will be performed once a month for a 3-month period. The results will be assessed by quartile scoring criteria; by comparing digital photos taken before and after each treatment; and also, by the measurement of cutaneous temperature, skin pH, and elasticity before and after the treatment. This paper describes the rationale and the design of the randomized controlled trial, which may provide evidence for clinical application of the methodology and the quality related to the efficacy and safety of fractional CO laser versus the FRF protocol for striae treatment.
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title Fractional CO 2 Laser versus Fractional Radiofrequency for Skin Striae Treatment: Study Protocol for a Randomized Controlled Trial
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