Development and challenges in the discovery of 5-HT 1A and 5-HT 7 receptor ligands

Serotonin (5-hydroxytryptamine) is a small molecule that acts both in the central and peripheral nervous system as a neurotransmitter and a hormone, respectively. Serotonin is synthesized via a multi-stage pathway beginning with l-tryptophan, which is converted by an enzyme called tryptophan hydroxy...

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Veröffentlicht in:	Bioorganic chemistry 2023-02, Vol.131, p.106254
Hauptverfasser:	Singh, Deepika, Singh, Priya, Srivastava, Pooja, Kakkar, Dipti, Pathak, Mallika, Tiwari, Anjani Kumar
Format:	Artikel
Sprache:	eng
Schlagworte:	Anxiety Binding Sites Brain - metabolism Humans Ligands Receptors, Serotonin - metabolism Serotonin - metabolism
Online-Zugang:	Volltext
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