The effects of crocetin on oxidative stress induced ARPE-19 cells by H 2 O 2

The anti-apoptotic and antioxidant effects of crocetin was aimed to investigate on the oxidative damage model of ARPE-19 cells. The oxidative damage in ARPE cells was developed by H O treatment at 800 μM. Different doses of crocetin (1-80 μM) were applied for 24 h, and the effects on viability were...

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Veröffentlicht in:	Experimental eye research 2023-01, Vol.226, p.109305
Hauptverfasser:	Demirci Kucuk, Kübra, Tokuc, Ecem Onder, Aciksari, Aysegul, Duruksu, Gokhan, Yazir, Yusufhan, Karabas, Veysel Levent
Format:	Artikel
Sprache:	eng
Schlagworte:	Antioxidants - metabolism Antioxidants - pharmacology Apoptosis Cell Line Cell Survival Glutathione - metabolism Hydrogen Peroxide - toxicity NF-E2-Related Factor 2 - metabolism Oxidative Stress Proto-Oncogene Proteins c-bcl-2 - genetics Proto-Oncogene Proteins c-bcl-2 - metabolism Reactive Oxygen Species - metabolism Superoxide Dismutase - metabolism
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