Impact of the selective A2 A R and A2 B R dual antagonist AB928/etrumadenant on CAR T cell function

Chimeric antigen receptor (CAR) T cell therapy has been successfully translated to clinical practice for the treatment of B cell malignancies. The suppressive microenvironment of many malignancies is a bottleneck preventing treatment success of CAR T cells in a broader range of tumours. Among others...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	British journal of cancer 2022-12, Vol.127 (12), p.2175
Hauptverfasser:	Seifert, Matthias, Benmebarek, Mohamed-Reda, Briukhovetska, Daria, Märkl, Florian, Dörr, Janina, Cadilha, Bruno L, Jobst, Jakob, Stock, Sophia, Andreu-Sanz, David, Lorenzini, Theo, Grünmeier, Ruth, Oner, Arman, Obeck, Hannah, Majed, Lina, Dhoqina, Dario, Feinendegen, Manouk, Gottschlich, Adrian, Zhang, Jin, Schindler, Ulrike, Endres, Stefan, Kobold, Sebastian
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine - pharmacology Animals Cytokines Mice Neoplasms T-Lymphocytes Tumor Microenvironment
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!