A ROS-responsive biomimetic nano-platform for enhanced chemo-photodynamic-immunotherapy efficacy

Due to the complex bloodstream components, tumor microenvironment and tumor heterogeneity, traditional nanoparticles have a limited effect (low drug delivery efficiency and poor penetration to the deeper tumor) on eradicating tumors. To solve these challenges, novel platelet membrane-coated nanopart...

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Veröffentlicht in:	Biomaterials science 2022-11, Vol.1 (22), p.6583-66
Hauptverfasser:	Yan, Huixian, Zhang, Yanan, Zhang, Yu, Li, Yingying, Kong, Xinru, Liu, Dongzhu, Li, Jin, Xi, Yanwei, Ji, Jianbo, Ye, Lei, Zhai, Guangxi
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Apoptosis Biomimetics Cell Line, Tumor Chemotherapy Heterogeneity Immune system Immunotherapy Immunotherapy - methods Lung Neoplasms - drug therapy Lungs Membranes Metastasis Micelles Nanoparticles Penetration Photochemotherapy - methods Photodynamic therapy Photosensitizing Agents - pharmacology Photosensitizing Agents - therapeutic use Polychlorinated Dibenzodioxins Rats Reactive Oxygen Species Suppressors Tumor Microenvironment Tumors
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