Research progress on the synthesis and pharmacology of 1,3,4-oxadiazole and 1,2,4-oxadiazole derivatives: a mini review

Oxadiazole is a five-membered heterocyclic compound containing two nitrogen atoms and one oxygen atom. The 1,3,4-oxadiazole and 1,2,4-oxadiazole have favourable physical, chemical, and pharmacokinetic properties, which significantly increase their pharmacological activity via hydrogen bond interacti...

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Veröffentlicht in:	Journal of enzyme inhibition and medicinal chemistry 2022-12, Vol.37 (1), p.2304-2319
Hauptverfasser:	Wang, Jing-Jing, Sun, Wen, Jia, Wei-Dong, Bian, Ming, Yu, Li-Jun
Format:	Artikel
Sprache:	eng
Schlagworte:	1,2,4-oxadiazole 1,3,4-oxadiazole activity Analgesics Anti-Bacterial Agents - pharmacology Antioxidants Binding sites Biological activity Cancer Cell growth Chemistry Chemistry Techniques, Synthetic Chemistry, Pharmaceutical Diabetes Diabetes mellitus Enzymes Inflammation Kinases Laboratories Nonsteroidal anti-inflammatory drugs Oxadiazole derivatives Oxadiazoles - chemistry Oxadiazoles - pharmacology Pharmaceutical sciences Pharmacokinetics Pharmacology Review synthesis
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