Intravitreal 5-Fluorouracil and Heparin to Prevent Proliferative Vitreoretinopathy: Results from a Randomized Clinical Trial

Proliferative vitreoretinopathy (PVR) is the major cause for surgical failure after primary rhegmatogenous retinal detachment (RRD). So far, no therapy has been proven to prevent PVR. Promising results for 5-fluorouracil (5-FU) and low-molecular weight heparin (LMWH) in high-risk eyes have been repo...

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Veröffentlicht in:	Ophthalmology (Rochester, Minn.) Minn.), 2022-10, Vol.129 (10), p.1129
Hauptverfasser:	Schaub, Friederike, Schiller, Petra, Hoerster, Robert, Kraus, Daria, Holz, Frank G, Guthoff, Rainer, Agostini, Hansjürgen, Spitzer, Martin S, Wiedemann, Peter, Lommatzsch, Albrecht, Boden, Karl T, Dimopoulos, Spyridon, Bemme, Sebastian, Tamm, Svenja, Maier, Mathias, Roider, Johann, Enders, Philip, Altay, Lebriz, Fauser, Sascha, Kirchhof, Bernd
Format:	Artikel
Sprache:	eng
Schlagworte:	Dalteparin - therapeutic use Double-Blind Method Fluorouracil Heparin - therapeutic use Heparin, Low-Molecular-Weight - therapeutic use Humans Retinal Detachment - surgery Vitrectomy - adverse effects Vitreoretinopathy, Proliferative - drug therapy Vitreoretinopathy, Proliferative - etiology Vitreoretinopathy, Proliferative - prevention & control
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