Severe and ChRonic ATopic Dermatitis CoHort (SCRATCH): A Danish Real-world Evidence Atopic Dermatitis Treatment Registry
Data from real-world use of new systemic treatments in atopic dermatitis (AD) is important for assessing safety and efficacy. The aim of this study is to de-scribe the baseline characteristics of adult patients with moderate-to-severe AD enrolled in the Danish nationwide Severe and ChRonic ATopic de...
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| Veröffentlicht in: | Acta dermato-venereologica 2022-06 |
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| creator | Hedegaard Pliess Larsen, Henrik Vittrup, Ida Frier Ruge, Iben Elberling, Jesper Skov, Lone Ibler, Kristina Borut Ernst Jemec, Gregor Gotthard Mørtz, Charlotte Overgaard Bach, Rasmus Bindslev-Jensen, Carsten Glud Dalager, Maiken Agner, Tove Deleuran, Mette Vestergaard, Christian Pontoppidan Thyssen, Jacob |
| description | Data from real-world use of new systemic treatments in atopic dermatitis (AD) is important for assessing safety and efficacy. The aim of this study is to de-scribe the baseline characteristics of adult patients with moderate-to-severe AD enrolled in the Danish nationwide Severe and ChRonic ATopic dermatitis CoHort (SCRATCH) database, between October 2017 and August 2021. A total of 282 adult patients were included. Most (62%) were men, the median age at baseline was 43 years (interquartile range (IQR) 29-54 years), and median age at onset of AD was 1 year (IQR 0-6 years). The median Eczema Area and Severity Index at treatment initiation was 19.1 (IQR 11.9-25.7); median Patient Oriented Eczema Measure 21.0 (IQR 16.0-25.0); median Dermatology Life Quality Index 13.0 (IQR 7.0-19.0); and median itch and sleep numerical rating scale scores 8.0 (IQR 6.0-9.0) and 6.0 (IQR 4.0-8.0). Differences were found between the sexes. This registry will provide a source for future efficacy and safety studies. |
| format | Article |
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| identifier | EISSN: 1651-2057 |
| ispartof | Acta dermato-venereologica, 2022-06 |
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| language | eng |
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| source | DOAJ Directory of Open Access Journals; EZB-FREE-00999 freely available EZB journals; PubMed Central; Alma/SFX Local Collection |
| title | Severe and ChRonic ATopic Dermatitis CoHort (SCRATCH): A Danish Real-world Evidence Atopic Dermatitis Treatment Registry |
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