Assessment of the inhalation exposure and incremental lifetime cancer risk of PM 2.5 bounded polycyclic aromatic hydrocarbons (PAHs) by different toxic equivalent factors and occupancy probability, in the case of Xi'an
Polycyclic aromatic hydrocarbons (PAHs) are widespread toxic pollutants in the atmosphere and have attracted much attention for decades. In this study, we compared the health risks of PAHs based on different toxic equivalent factors (TEFs) in a heavily polluted area during heating and non-heating pe...
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Veröffentlicht in: | Environmental science and pollution research international 2022-10, Vol.29 (50), p.76378 |
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creator | Wang, Yumeng Wang, Zedong Wang, Jingzhi Wang, Runyu Ding, Xinxin Donahue, Neil McPherson Dong, Zhibao Ma, Ge Han, Yongming Cao, Junji |
description | Polycyclic aromatic hydrocarbons (PAHs) are widespread toxic pollutants in the atmosphere and have attracted much attention for decades. In this study, we compared the health risks of PAHs based on different toxic equivalent factors (TEFs) in a heavily polluted area during heating and non-heating periods. We also pay attention to occupancy probability (OP) in different polluted areas. The results showed that there were big differences for calculations by different TEFs, and also by OP or not. Age groups except adults were all lower calculated by OP than not. The sensitivity analysis results on the incremental lifetime cancer risks (ILCR) for population groups by Monte Carlo simulation identified that the cancer slope factor extremely affected the health risk assessment in heating periods, followed by daily inhalation exposure levels. However, daily inhalation exposure levels have dominated the effect on the inhalation ILCR and then followed by the cancer slope factor in non-heating periods. The big differences by different calculations investigated that it is important to set up the correlations between the pollution level and health risks, especially for the longtime health assessment. |
doi_str_mv | 10.1007/s11356-022-21061-9 |
format | Article |
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In this study, we compared the health risks of PAHs based on different toxic equivalent factors (TEFs) in a heavily polluted area during heating and non-heating periods. We also pay attention to occupancy probability (OP) in different polluted areas. The results showed that there were big differences for calculations by different TEFs, and also by OP or not. Age groups except adults were all lower calculated by OP than not. The sensitivity analysis results on the incremental lifetime cancer risks (ILCR) for population groups by Monte Carlo simulation identified that the cancer slope factor extremely affected the health risk assessment in heating periods, followed by daily inhalation exposure levels. However, daily inhalation exposure levels have dominated the effect on the inhalation ILCR and then followed by the cancer slope factor in non-heating periods. The big differences by different calculations investigated that it is important to set up the correlations between the pollution level and health risks, especially for the longtime health assessment.</description><identifier>EISSN: 1614-7499</identifier><identifier>DOI: 10.1007/s11356-022-21061-9</identifier><identifier>PMID: 35668257</identifier><language>eng</language><publisher>Germany</publisher><subject>Adult ; Air Pollutants - analysis ; China - epidemiology ; Environmental Monitoring ; Humans ; Inhalation Exposure - analysis ; Neoplasms - chemically induced ; Neoplasms - epidemiology ; Particulate Matter - analysis ; Polycyclic Aromatic Hydrocarbons - analysis ; Probability ; Risk Assessment</subject><ispartof>Environmental science and pollution research international, 2022-10, Vol.29 (50), p.76378</ispartof><rights>2022. 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In this study, we compared the health risks of PAHs based on different toxic equivalent factors (TEFs) in a heavily polluted area during heating and non-heating periods. We also pay attention to occupancy probability (OP) in different polluted areas. The results showed that there were big differences for calculations by different TEFs, and also by OP or not. Age groups except adults were all lower calculated by OP than not. The sensitivity analysis results on the incremental lifetime cancer risks (ILCR) for population groups by Monte Carlo simulation identified that the cancer slope factor extremely affected the health risk assessment in heating periods, followed by daily inhalation exposure levels. However, daily inhalation exposure levels have dominated the effect on the inhalation ILCR and then followed by the cancer slope factor in non-heating periods. The big differences by different calculations investigated that it is important to set up the correlations between the pollution level and health risks, especially for the longtime health assessment.</description><subject>Adult</subject><subject>Air Pollutants - analysis</subject><subject>China - epidemiology</subject><subject>Environmental Monitoring</subject><subject>Humans</subject><subject>Inhalation Exposure - analysis</subject><subject>Neoplasms - chemically induced</subject><subject>Neoplasms - epidemiology</subject><subject>Particulate Matter - analysis</subject><subject>Polycyclic Aromatic Hydrocarbons - analysis</subject><subject>Probability</subject><subject>Risk Assessment</subject><issn>1614-7499</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkD1PwzAQhi0kRMvHH2BAtwESKbbbJmSsEKgLUgcGtspxLqrBsYPPQfVf5deQVDAznfTqee8eHWOXgs8E58U9CTFf5hmXMpOC5yIrj9hU5GKRFYuynLBTonfOJS9lccImA5o_yGUxZd8rIiRq0UXwDcQdgnE7ZVU03gHuO099QFCuHnIdcASVBWsajKZF0MppDBAMfYz9zQvI2RIq37saa-i8TTppazSo4NthqYZdqoPXKlTeEdxsVmu6hSpBbZoGw6gR_X7A8LM3X8qOQaN09IEOEl7rvhtuJuiCr1RlrInpbnA7qGtFOGq8mWvlztlxoyzhxe88Y1fPT6-P66zrqxbrbRdMq0La_j1j_i_wA0hhdHk</recordid><startdate>202210</startdate><enddate>202210</enddate><creator>Wang, Yumeng</creator><creator>Wang, Zedong</creator><creator>Wang, Jingzhi</creator><creator>Wang, Runyu</creator><creator>Ding, Xinxin</creator><creator>Donahue, Neil McPherson</creator><creator>Dong, Zhibao</creator><creator>Ma, Ge</creator><creator>Han, Yongming</creator><creator>Cao, Junji</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope></search><sort><creationdate>202210</creationdate><title>Assessment of the inhalation exposure and incremental lifetime cancer risk of PM 2.5 bounded polycyclic aromatic hydrocarbons (PAHs) by different toxic equivalent factors and occupancy probability, in the case of Xi'an</title><author>Wang, Yumeng ; Wang, Zedong ; Wang, Jingzhi ; Wang, Runyu ; Ding, Xinxin ; Donahue, Neil McPherson ; Dong, Zhibao ; Ma, Ge ; Han, Yongming ; Cao, Junji</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-pubmed_primary_356682573</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Adult</topic><topic>Air Pollutants - analysis</topic><topic>China - epidemiology</topic><topic>Environmental Monitoring</topic><topic>Humans</topic><topic>Inhalation Exposure - analysis</topic><topic>Neoplasms - chemically induced</topic><topic>Neoplasms - epidemiology</topic><topic>Particulate Matter - analysis</topic><topic>Polycyclic Aromatic Hydrocarbons - analysis</topic><topic>Probability</topic><topic>Risk Assessment</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Wang, Yumeng</creatorcontrib><creatorcontrib>Wang, Zedong</creatorcontrib><creatorcontrib>Wang, Jingzhi</creatorcontrib><creatorcontrib>Wang, Runyu</creatorcontrib><creatorcontrib>Ding, Xinxin</creatorcontrib><creatorcontrib>Donahue, Neil McPherson</creatorcontrib><creatorcontrib>Dong, Zhibao</creatorcontrib><creatorcontrib>Ma, Ge</creatorcontrib><creatorcontrib>Han, Yongming</creatorcontrib><creatorcontrib>Cao, Junji</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><jtitle>Environmental science and pollution research international</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Wang, Yumeng</au><au>Wang, Zedong</au><au>Wang, Jingzhi</au><au>Wang, Runyu</au><au>Ding, Xinxin</au><au>Donahue, Neil McPherson</au><au>Dong, Zhibao</au><au>Ma, Ge</au><au>Han, Yongming</au><au>Cao, Junji</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Assessment of the inhalation exposure and incremental lifetime cancer risk of PM 2.5 bounded polycyclic aromatic hydrocarbons (PAHs) by different toxic equivalent factors and occupancy probability, in the case of Xi'an</atitle><jtitle>Environmental science and pollution research international</jtitle><addtitle>Environ Sci Pollut Res Int</addtitle><date>2022-10</date><risdate>2022</risdate><volume>29</volume><issue>50</issue><spage>76378</spage><pages>76378-</pages><eissn>1614-7499</eissn><abstract>Polycyclic aromatic hydrocarbons (PAHs) are widespread toxic pollutants in the atmosphere and have attracted much attention for decades. In this study, we compared the health risks of PAHs based on different toxic equivalent factors (TEFs) in a heavily polluted area during heating and non-heating periods. We also pay attention to occupancy probability (OP) in different polluted areas. The results showed that there were big differences for calculations by different TEFs, and also by OP or not. Age groups except adults were all lower calculated by OP than not. The sensitivity analysis results on the incremental lifetime cancer risks (ILCR) for population groups by Monte Carlo simulation identified that the cancer slope factor extremely affected the health risk assessment in heating periods, followed by daily inhalation exposure levels. However, daily inhalation exposure levels have dominated the effect on the inhalation ILCR and then followed by the cancer slope factor in non-heating periods. The big differences by different calculations investigated that it is important to set up the correlations between the pollution level and health risks, especially for the longtime health assessment.</abstract><cop>Germany</cop><pmid>35668257</pmid><doi>10.1007/s11356-022-21061-9</doi></addata></record> |
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source | MEDLINE; Springer Nature - Complete Springer Journals |
subjects | Adult Air Pollutants - analysis China - epidemiology Environmental Monitoring Humans Inhalation Exposure - analysis Neoplasms - chemically induced Neoplasms - epidemiology Particulate Matter - analysis Polycyclic Aromatic Hydrocarbons - analysis Probability Risk Assessment |
title | Assessment of the inhalation exposure and incremental lifetime cancer risk of PM 2.5 bounded polycyclic aromatic hydrocarbons (PAHs) by different toxic equivalent factors and occupancy probability, in the case of Xi'an |
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