Inhibition of Lipopolysaccharide-Induced Inflammatory Signaling by Soft Coral-Derived Prostaglandin A 2 in RAW264.7 Cells

Lipopolysaccharide (LPS) is a component of the outer membrane of Gram-negative bacteria and causes inflammatory diseases. We searched MeOH extracts of collected marine organisms for inhibitors of LPS-induced nitric oxide (NO) production in RAW264.7 cells and identified prostaglandin A (PGA ) as an a...

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Veröffentlicht in:	Marine drugs 2022-05, Vol.20 (5)
Hauptverfasser:	Ohno, Osamu, Mizuno, Eika, Miyamoto, Junichiro, Hoshina, Tomoyuki, Sano, Takuya, Matsuno, Kenji
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Anthozoa - metabolism Lipopolysaccharides - metabolism Lipopolysaccharides - pharmacology Macrophages Mice NF-kappa B - metabolism Nitric Oxide - metabolism
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