Enzymatically amplified linear dbDNA TM as a rapid and scalable solution to industrial lentiviral vector manufacturing

Traditional bacterial fermentation techniques used to manufacture plasmid are time-consuming, expensive, and inherently unstable. The production of sufficient GMP grade material thus imposes a major bottleneck on industrial-scale manufacturing of lentiviral vectors (LVV). Touchlight's linear do...

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Veröffentlicht in:	Gene therapy 2023-02, Vol.30 (1-2), p.122
Hauptverfasser:	Barreira, Maria, Kerridge, Claire, Jorda, Sara, Olofsson, Didrik, Neumann, Alexander, Horton, Helen, Smith-Moore, Sarah
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA Genetic Vectors - genetics Lentivirus - genetics Plasmids - genetics Transfection
Online-Zugang:	Volltext
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