Shikonin combined with methotrexate regulate macrophage polarization to treat psoriasis

This study aimed to investigate whether shikonin combined with methotrexate could inhibit psoriasis progression by regulating the polarization of macrophages through in vivo and in vitro experiments. Imiquimod was administrated to the exposed skin of BALB/c mice, and shikonin and methotrexate suspen...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Bioengineered 2022-04, Vol.13 (4), p.11146-11155
Hauptverfasser:	Tao, Tingjun, Chen, Yan, Lai, Bochen, Wang, Jinhua, Wang, Weiliang, Xiao, Weimian, Cha, Xushan
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Imiquimod - adverse effects Lipopolysaccharides macrophage polarization Macrophages - pathology methotrexate Methotrexate - adverse effects Mice Naphthoquinones psoriasis Psoriasis - drug therapy Research Paper Shikonin
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!