Increased expression of TIGIT and KLRG1 correlates with impaired CD56 bright NK cell immunity in HPV16-related cervical intraepithelial neoplasia

The onset and progression of cervical intraepithelial neoplasia (CIN) are closely associated with the persistent infection of high-risk HPV (especially type16), which is mainly caused by immune escape. Natural killer (NK) cells play an important role against virally infected cells and tumor cells th...

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Veröffentlicht in:	Virology journal 2022-04, Vol.19 (1), p.68
Hauptverfasser:	Nie, You, Liu, Dandan, Yang, Wen, Li, Yazhuo, Zhang, Lihua, Cheng, Xia, Chen, Ruyu, Yuan, Bingbing, Zhang, Guangzheng, Wang, Hongwei
Format:	Artikel
Sprache:	eng
Schlagworte:	Cervical Intraepithelial Neoplasia Female Human papillomavirus 16 Humans Killer Cells, Natural Lectins, C-Type - genetics Leukocytes, Mononuclear - metabolism Ligands Papillomavirus Infections - pathology Receptors, Immunologic - metabolism Sialic Acid Binding Immunoglobulin-like Lectins Uterine Cervical Neoplasms
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