Caveolin-3 prevents swelling-induced membrane damage via regulation of I Cl,swell activity

Caveola membrane structures harbor mechanosensitive chloride channels (MCCs; including chloride channel 2, chloride channel 3, and SWELL1, also known as LRRC8A) that form a swelling-activated chloride current (I ) and play an important role in cell volume regulation and mechanoelectrical signal tran...

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Veröffentlicht in:	Biophysical journal 2022-05, Vol.121 (9), p.1643
Hauptverfasser:	Turner, Daniel G P, Tyan, Leonid, DeGuire, Frank C, Medvedev, Roman Y, Stroebel, Sami J, Lang, Di, Glukhov, Alexey V
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Butyric Acid Caveolin 3 - metabolism Cell Size Chloride Channels - metabolism Chlorides - metabolism HEK293 Cells Humans Membrane Proteins - metabolism Mice
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