Colorectal Cancer-Derived Small Extracellular Vesicles Promote Tumor Immune Evasion by Upregulating PD-L1 Expression in Tumor-Associated Macrophages

Tumor-associated macrophages (TAMs) are one of the most abundant cell types in colorectal cancer (CRC) tumor microenvironment (TME). Recent studies observed complicated "cross-talks" between cancer cells and macrophages in TME. However, the underlying mechanisms are still poorly elucidated...

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Veröffentlicht in:Advanced science 2022-03, Vol.9 (9), p.2102620
Hauptverfasser: Yin, Yuan, Liu, Bingxin, Cao, Yulin, Yao, Surui, Liu, Yuhang, Jin, Guoying, Qin, Yan, Chen, Ying, Cui, Kaisa, Zhou, Leyuan, Bian, Zehua, Fei, Bojian, Huang, Shenglin, Huang, Zhaohui
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Sprache:eng
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