IgG response to SARS-CoV-2 and seasonal coronaviruses contributes to complement overactivation in severe COVID-19 patients

Excessive complement activation has been implicated in the pathogenesis of COVID-19, but the mechanisms leading to this response remain unclear. We measured plasma levels of key complement markers, SARS-CoV-2 RNA and antibodies against SARS-CoV-2 and common cold coronaviruses (CCC) in hospitalized p...

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Veröffentlicht in:	The Journal of infectious diseases 2022-03
Hauptverfasser:	Castanha, Priscila M S, Tuttle, Dylan J, Kitsios, Georgios D, Jacobs, Jana L, Braga-Neto, Ulisses, Duespohl, Matthew, Rathod, Sanjay, Marti, Michelle M, Wheeler, Sarah, Naqvi, Asma, Staines, Brittany, Mellors, John, Morris, Alison, McVerry, Bryan J, Shah, Faraaz, Schaefer, Caitlin, Macatangay, Bernard J C, Methe, Barbara, Fernandez, Christian A, Barratt-Boyes, Simon M, Burke, Donald, Marques, Ernesto T A
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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