Marrow-Derived Autologous Stromal Cells for the Restoration of Salivary Hypofunction (MARSH): Study protocol for a phase 1 dose-escalation trial of patients with xerostomia after radiation therapy for head and neck cancer: MARSH: Marrow-Derived Autologous Stromal Cells for the Restoration of Salivary Hypofunction

Xerostomia, or dry mouth, is a common side effect of head and neck radiation. Current treatment options for radiation-induced xerostomia are generally supportive in nature. Adult stem cells are the ultimate source for replenishment of salivary gland tissue. Bone marrow-derived mesenchymal stromal ce...

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Veröffentlicht in:	Cytotherapy (Oxford, England) England), 2022-05, Vol.24 (5), p.534
Hauptverfasser:	Blitzer, Grace C, Rogus-Pulia, Nicole M, Mattison, Ryan J, Varghese, Tomy, Ganz, Olga, Chappell, Richard, Galipeau, Jacques, McDowell, Kimberly A, Meyers, Ross O, Glazer, Tiffany A, Kimple, Randall J
Format:	Artikel
Sprache:	eng
Schlagworte:	Bone Marrow Clinical Trials, Phase I as Topic Head and Neck Neoplasms - radiotherapy Humans Mesenchymal Stem Cells Quality of Life Radiation Injuries - therapy Transplantation, Autologous Wetlands Xerostomia - etiology Xerostomia - therapy
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