A Palette of Fluorescent A β 42 Peptides Labelled at a Range of Surface-Exposed Sites

Fluorescence-based single molecule techniques provide important tools towards understanding the molecular mechanism of complex neurodegenerative diseases. This requires efficient covalent attachment of fluorophores. Here we create a series of cysteine mutants (S8C, Y10C, S26C, V40C, and A42C) of Aβ4...

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Veröffentlicht in:	International journal of molecular sciences 2022-02, Vol.23 (3)
Hauptverfasser:	Thacker, Dev, Bless, Mara, Barghouth, Mohammad, Zhang, Enming, Linse, Sara
Format:	Artikel
Sprache:	eng
Schlagworte:	Alzheimer Disease - metabolism Amyloid beta-Peptides - chemistry Amyloid beta-Peptides - metabolism Fluorescent Dyes - chemistry Humans Models, Molecular Peptide Fragments - chemistry Peptide Fragments - metabolism
Online-Zugang:	Volltext
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